Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease - Wikidata - wikimedia - TriplyDB

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

http://www.wikidata.org/entity/Q42177330

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Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2 Determinant Variables, Enteric Pathogen Burden, Gut Function, and Immune-Related Inflammatory Biomarkers Associated with Childhood Malnutrition: A Prospective Case-Control Study in Northeastern Brazil.DMBT1 expression in biliary carcinogenesis with correlation of clinicopathological data.Establishment a real-time reverse transcription PCR based on host biomarkers for the detection of the subclinical cases of Mycobacterium avium subsp. paratuberculosis.Correlations between skin lesions induced by anti-tumor necrosis factor-α and selected cytokines in Crohn's disease patients High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesity Validation of gene expression biomarker analysis for biopsy-based clinical trials in Crohn's disease Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.Combining patient proteomics and in vitro cardiomyocyte phenotype testing to identify potential mediators of heart failure with preserved ejection fraction.ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.Lipocalin 2 prevents intestinal inflammation by enhancing phagocytic bacterial clearance in macrophages.Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis CCL20 Is Negatively Regulated by TGF-β1 in Intestinal Epithelial Cells and Reduced in Crohn's Disease Patients With a Successful Response to Mongersen, a Smad7 Antisense Oligonucleotide.Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response.β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner.Hypoxia-inducible factor-1α regulates microglial functions affecting neuronal survival in the acute phase of ischemic stroke in mice.Fecal Lipocalin-2 as a Sensitive and Noninvasive Biomarker in the TNBS Crohn's Inflammatory Bowel Disease Model.Neutrophil gelatinase-associated lipocalin in blood in children with inflammatory bowel disease.Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

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Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

http://www.wikidata.org/entity/Q42177330

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

@en

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

@nl

type

label

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

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Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

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prefLabel

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

@en

Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

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Clinical and translational gastroenterology

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Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

@en

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Barbara Joyce-Shaikh

http://www.w3.org/2001/XMLSchema#string

Beth Basham

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Brent S McKenzie

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Charles O Elson

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Corinne Cayatte

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Daniel Cua

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Edward P Bowman

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Erin Murphy

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Felix Vega

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Jeffrey Grein

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P2860

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

The role of the novel Th17 cytokine IL-26 in intestinal inflammation

Interleukin-23 drives innate and T cell-mediated intestinal inflammation

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q

Development, cytokine profile and function of human interleukin 17-producing helper T cells

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

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e10

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10.1038/CTG.2012.2

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3

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René de Waal Malefyt

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2012-02-16T00:00:00Z

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233913804

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23238132

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inflammatory bowel diseases

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3365674

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