Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells.
about
Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits pancreatic cancer cell proliferation and induces apoptosis via the EGFR pathway and caspase signaling.Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example.Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death.Distinct cargo-specific response landscapes underpin the complex and nuanced role of galectin-glycan interactions in clathrin-independent endocytosis.Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes.
P2860
Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Metabolic flux-driven sialylat ...... W1990 pancreatic cancer cells.
@en
Metabolic flux-driven sialylat ...... W1990 pancreatic cancer cells.
@nl
type
label
Metabolic flux-driven sialylat ...... W1990 pancreatic cancer cells.
@en
Metabolic flux-driven sialylat ...... W1990 pancreatic cancer cells.
@nl
prefLabel
Metabolic flux-driven sialylat ...... W1990 pancreatic cancer cells.
@en
Metabolic flux-driven sialylat ...... W1990 pancreatic cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
Metabolic flux-driven sialylat ...... SW1990 pancreatic cancer cells
@en
P2093
Christopher T Saeui
Elaine Tan
Kevin J Yarema
Rahul Bhattacharya
Samuel Sklar
P2860
P304
66491-66511
P356
10.18632/ONCOTARGET.11582
P407
P577
2016-10-01T00:00:00Z