The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.
about
Evidence against T-cell development in the adult human intestinal mucosa based upon lack of terminal deoxynucleotidyltransferase expressionInterleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytesThe role of the gut as a primary lymphoid organ: CD8αα intraepithelial T lymphocytes in euthymic mice derive from very immature CD44+ thymocyte precursorsEvidence of the extrathymic development of tyrosinase-related protein-2-recognizing CD8+ T cells with low avidityαβT cell receptors expressed by CD4(-)CD8αβ(-) intraepithelial T cells drive their fate into a unique lineage with unusual MHC reactivities.gamma delta cells in gut infection, immunopathology, and organogenesis.Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cellsElevated T cell receptor signaling identifies a thymic precursor to the TCRαβ(+)CD4(-)CD8β(-) intraepithelial lymphocyte lineage.Extracellular domains of CD8α and CD8ß subunits are sufficient for HLA class I restricted helper functions of TCR-engineered CD4(+) T cells.Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHCFemale sex hormones as regulatory factors in the vaginal immune compartment.Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance.Regulatory T cells: peace keepers in the gut.In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues.Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.Oligoclonality of human intestinal intraepithelial T cells.Mechanism of self-tolerance of gamma/delta T cells in epithelial tissue.Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytesThe surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.Peripheral engraftment of fetal intestine into athymic mice sponsors T cell development: direct evidence for thymopoietic function of murine small intestineIntestinal intraepithelial lymphocytes include precursors committed to the T cell receptor alpha beta lineage.Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally. Correlation between functional assays, presence of perforin and granzyme transcripts, and cytoplasmic granules.Tolerance of T cell receptor gamma/delta cells in the intestine.High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytesHeterogeneity and biased T cell receptor alpha/beta repertoire of mucosal CD8+ cells from murine large intestine: implications for functional state.Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiationThymic and extrathymic origins of gut intraepithelial lymphocyte populations in miceIntestinal intraepithelial lymphocytes: the plot thickens.Immune deviation of 2C transgenic intraepithelial lymphocytes in antigen-bearing hosts.c-kit+ stem cells and thymocyte precursors in the livers of adult mice.Whence the intestinal intraepithelial lymphocyte?A unique subset of self-specific intraintestinal T cells maintains gut integrity.Characterization of T cell differentiation in the murine gut.Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice.Positive selection of extrathymically developed T cells by self-antigensEnterocyte expression of interleukin 7 induces development of gammadelta T cells and Peyer's patches.The Tower of Babel of CD8+ T-cell memory: known facts, deserted roads, muddy waters, and possible dead ends.Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptorsgammadelta T cells: firefighters or fire boosters in the front lines of inflammatory responses.Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine.
P2860
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P2860
The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
The V beta repertoire of mouse ...... way of T cell differentiation.
@en
The V beta repertoire of mouse ...... way of T cell differentiation.
@nl
type
label
The V beta repertoire of mouse ...... way of T cell differentiation.
@en
The V beta repertoire of mouse ...... way of T cell differentiation.
@nl
prefLabel
The V beta repertoire of mouse ...... way of T cell differentiation.
@en
The V beta repertoire of mouse ...... way of T cell differentiation.
@nl
P2093
P2860
P356
P1476
The V beta repertoire of mouse ...... way of T cell differentiation.
@en
P2093
P2860
P304
P356
10.1084/JEM.173.2.483
P407
P577
1991-02-01T00:00:00Z