Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst.
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Insights into the Reaction of Protein-tyrosine Phosphatase 1B: CRYSTAL STRUCTURES FOR TRANSITION STATE ANALOGS OF BOTH CATALYTIC STEPSA Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme ActivationAb initio path-integral calculations of kinetic and equilibrium isotope effects on base-catalyzed RNA transphosphorylation models.Kinetic isotope effects in asymmetric reactionsEffect of Zn2+ binding and enzyme active site on the transition state for RNA 2'-O-transphosphorylation interpreted through kinetic isotope effects.Experimental and computational analysis of the transition state for ribonuclease A-catalyzed RNA 2'-O-transphosphorylation.Altered (transition) states: mechanisms of solution and enzyme catalyzed RNA 2'-O-transphosphorylationIntegration of kinetic isotope effect analyses to elucidate ribonuclease mechanism.Isotope effect analyses provide evidence for an altered transition state for RNA 2'-O-transphosphorylation catalyzed by Zn(2+).Kinetic isotope effects for RNA cleavage by 2'-O- transphosphorylation: nucleophilic activation by specific base.On the question of stepwise vs. concerted cleavage of RNA models promoted by a synthetic dinuclear Zn(II) complex in methanol: implementation of a noncleavable phosphonate probe.Catalytic signal amplification for the discrimination of ATP and ADP using functionalised gold nanoparticles.Phosphodiester models for cleavage of nucleic acids.Chiral Nanozymes-Gold Nanoparticle-Based Transphosphorylation Catalysts Capable of Enantiomeric Discrimination.There is no universal mechanism for the cleavage of RNA model compounds in the presence of metal ion catalysts.Cleavage of RNA phosphodiester bonds by small molecular entities: a mechanistic insight.βLGvalues in mechanistic studies on the transesterification of RNA models and their application in a metal ion complex promoted transesterificationThe Mechanism of Cleavage and Isomerisation of RNA Promoted by an Efficient Dinuclear Zn2+ Complex
P2860
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P2860
Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc
@nl
Altered transition state for t ...... a dinuclear zinc(II) catalyst.
@en
type
label
Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc
@nl
Altered transition state for t ...... a dinuclear zinc(II) catalyst.
@en
prefLabel
Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc
@nl
Altered transition state for t ...... a dinuclear zinc(II) catalyst.
@en
P2093
P2860
P50
P356
P1476
Altered transition state for t ...... a dinuclear zinc(II) catalyst.
@en
P2093
Janet R Morrow
Olga Iranzo
Subashree Iyer
Tim Humphry
P2860
P304
17858-17866
P356
10.1021/JA8059864
P407
P577
2008-12-01T00:00:00Z