Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site.
about
Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavitiesA Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude)Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface.5-HT(3) receptors.Noncompetitive Inhibition of 5-HT3 Receptors by Citral, Linalool, and Eucalyptol Revealed by Nonlinear Mixed-Effects Modeling.Discriminating between 5-HT₃A and 5-HT₃AB receptorsTwo distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.Novel mechanism of modulation at a ligand-gated ion channel; action of 5-Cl-indole at the 5-HT3 A receptor.The effect of Δ9-tetrahydrocannabinol, cannabidiol, menthol and propofol on 5-hydroxytryptamine type 3 eeceptors--a computational approach.Subunit-dependent inhibition and potentiation of 5-HT3 receptor by the anticancer drug, topotecan.
P2860
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P2860
Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@en
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@nl
type
label
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@en
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@nl
prefLabel
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@en
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@nl
P2093
P2860
P356
P1476
Discovery of a novel allosteri ...... ansmembrane intersubunit site.
@en
P2093
Kasper Harpsøe
Louise M Rahr
Philip K Ahring
Sarah B Thygesen
Sarah M Trattnig
Thomas Balle
P2860
P304
25241-25254
P356
10.1074/JBC.M112.360370
P407
P577
2012-05-15T00:00:00Z