Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling.
about
Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery.Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.Isocyclopamine, a novel synthetic derivative of cyclopamine, reverts doxorubicin resistance in MCF-7/ADR cells by increasing intracellular doxorubicin accumulation and downregulating breast cancer stem-like cells.C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog.Lewis Acid Mediated Nazarov Cyclization as a Convergent and Enantioselective Entry to C-nor-D-homo-Steroids.
P2860
Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@en
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@nl
type
label
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@en
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@nl
prefLabel
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@en
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@nl
P2093
P2860
P356
P1476
Cyclopamine analogs bearing ex ...... ibitors of hedgehog signaling.
@en
P2093
Anna Chentsova
Athanassios Giannis
Irene Rovardi
Johann Moschner
Nicole Eilert
Philipp Heretsch
P2860
P304
P356
10.3762/BJOC.9.267
P577
2013-10-31T00:00:00Z