AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis. - Wikidata - wikimedia - TriplyDB

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

http://www.wikidata.org/entity/Q42269205

about

AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours mTOR signaling in tumorigenesis Dissecting the role of AMP-activated protein kinase in human diseases.Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer.AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts.Targeting AMPK for cancer prevention and treatment.AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma.Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling.Identifying molecular drivers of gastric cancer through next-generation sequencing.AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin.AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms.AMPKα1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2.The mitochondrial H(+)-ATP synthase and the lipogenic switch: new core components of metabolic reprogramming in induced pluripotent stem (iPS) cells.AMPK: a contextual oncogene or tumor suppressor?Lessons from Nature: Sources and Strategies for Developing AMPK Activators for Cancer Chemotherapeutics The double-edged sword of AMPK signaling in cancer and its therapeutic implications.Targeting the 5'-AMP-activated protein kinase and related metabolic pathways for the treatment of prostate cancer.AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27.Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms.A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer.A RAS-CaMKKβ-AMPKα2 pathway promotes senescence by licensing post-translational activation of C/EBPβ through a novel 3'UTR mechanism.

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P2860

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

http://www.wikidata.org/entity/Q42269205

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

@zh-cn

name

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

@en

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

@nl

type

label

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

@en

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

@nl

prefLabel

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

@en

AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

@nl

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AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

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Charan V Devarakonda

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Kathryn N Phoenix

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Kevin P Claffey

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Laura E Stevens

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Melissa M Fox

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P2860

Hallmarks of Cancer: The Next Generation

Mammalian AMP-activated protein kinase subfamily

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Creation of human tumour cells with defined genetic elements

The INK4a/ARF network in tumour suppression

LKB1--a master tumour suppressor of the small intestine and beyond

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

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10.1177/1947601912452883

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