about
Killing activity of neutrophils is mediated through activation of proteases by K+ fluxImmunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cellsRedirection of B cell responsiveness by transforming growth factor beta receptorAbsence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signalingGranulocyte function in grancalcin-deficient miceImpaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin GImmunological development and cardiovascular function are normal in annexin VI null mutant micePatterned variation in murine MHC promoters.Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice.Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning.Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis.Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins.Conditional mutagenesis reveals immunological functions of widely expressed genes: activation thresholds, homeostatic mechanisms and disease models.TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution.Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.Key roles for transforming growth factor beta in melanocyte stem cell maintenanceInterruption of coding sequences by heterologous introns can enhance the functional expression of recombinant genes.Catalase negative Staphylococcus aureus retain virulence in mouse model of chronic granulomatous disease.Enhancer-deleted retroviral vectors restore high levels of superoxide generation in a mouse model of CGD.A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene.Expression and alternative processing of IL-18 in human neutrophils.Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants.Evidence that neutrophil elastase-deficient mice are resistant to bleomycin-induced fibrosis.C-terminal SRC kinase controls acute inflammation and granulocyte adhesion.TGFbeta type II receptor signaling controls Schwann cell death and proliferation in developing nerves.Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.Targeted disruption of the V(H) 81X gene: influence on the B cell repertoire.Differential roles of macrophages in diverse phases of skin repair.Conditional gene targetingMouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient miceThe role of grancalcin in adhesion of neutrophilsSelective ablation of v integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature deathV gene rearrangement is required to fully activate the hypermutation mechanism in B cellsTGF-beta receptor controls B cell responsiveness and induction of IgA in vivoAnimal models in biomedical research: transgenesis and gene targetingTGF-beta receptor signaling is critical for mucosal IgA responses
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Jürgen Roes
@ast
Jürgen Roes
@en
Jürgen Roes
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Jürgen Roes
@nl
Jürgen Roes
@sl
type
label
Jürgen Roes
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Jürgen Roes
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Jürgen Roes
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Jürgen Roes
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Jürgen Roes
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prefLabel
Jürgen Roes
@ast
Jürgen Roes
@en
Jürgen Roes
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Jürgen Roes
@nl
Jürgen Roes
@sl
P106
P21
P31
P496
0000-0003-3235-2345