Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

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Genetics of Severe Obesity

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Q58766920-39AB03E6-8278-4120-9626-461ED3471169

P2860

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

@en

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

@nl

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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

@en

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

@nl

P1476

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

@en

P2093

Danielle Frodyma

http://www.w3.org/2001/XMLSchema#string

Diane Costanzo-Garvey

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P2860

Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

KSR, a novel protein kinase required for RAS signal transduction

Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF

Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2

Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling

Oncogenic BRAF Deletions That Function as Homodimers and Are Sensitive to Inhibition by RAF Dimer Inhibitor LY3009120.

A dimerization-dependent mechanism drives RAF catalytic activation.

Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway

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1621

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P31

scholarly article

P356

10.12688/F1000RESEARCH.11895.1

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P478

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P50

Kurt Fisher

Beth K Neilsen

Robert E Lewis

P577

2017-08-31T00:00:00Z

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P698

29026529

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P932

5583734

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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

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P2860

P2860

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

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P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P698

P932