about
Super-resolution imaging strategies for cell biologists using a spinning disk microscopeBardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerizationLithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signalingStem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics.Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression.Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels.Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death.Confocal analysis of local and cellular strains in chondrocyte-agarose constructs subjected to mechanical shear.Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain.Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes.An improved confocal FRAP technique for the measurement of long-term actin dynamics in individual stress fibers.Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis.Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading.Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations.Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes.The shape of the urine stream--from biophysics to diagnosticsStent encrustation in feline and human artificial urine: does the low molecular weight composition account for the difference?Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult.Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1βBiomechanical analysis of structural deformation in living cells.Zonal variation in primary cilia elongation correlates with localized biomechanical degradation in stress deprived tendon.Stem cell mechanobiology.IFT88 influences chondrocyte actin organization and biomechanics.Differential effects of LifeAct-GFP and actin-GFP on cell mechanics assessed using micropipette aspiration.Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes.The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity.Temporal changes in cytoskeletal organisation within isolated chondrocytes quantified using a novel image analysis technique.Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields.Mitochondrial dynamics in chondrocytes and their connection to the mechanical properties of the cytoplasm.Experimental validation of a flat punch indentation methodology calibrated against unconfined compression tests for determination of soft tissue biomechanics.Reduced primary cilia length and altered Arl13b expression are associated with deregulated chondrocyte Hedgehog signaling in alkaptonuria.Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium.Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage.Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1β-mediated cartilage degradation.Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation.Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells.Viscoelastic cell mechanics and actin remodelling are dependent on the rate of applied pressure.Primary cilia elongation in response to interleukin-1 mediates the inflammatory response.Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment.Lithium chloride prevents interleukin-1β induced cartilage degradation and loss of mechanical properties.
P50
Q27306729-DA4B1840-4F34-429D-9D80-FEFE036390F5Q28511839-8574F14F-F035-46F6-BE75-84E7C6E0E500Q28576848-189323B9-90D1-4AE8-A6F5-F0F8D77738C4Q30604753-9F317A5D-EA18-48DE-8C2C-6529A64CF827Q30658095-48D4D17A-3213-4682-90B9-A446015EE6D9Q30828825-76FFFAD1-4B94-4586-8259-9AE6F6A624BEQ30908047-C5F288C9-8076-469B-8C55-C5DE28BF7AE7Q31094873-F7B9D5F9-9504-42F4-A1BF-51350B1BD33CQ33205273-D0D8CDAA-FD99-4E14-B458-C42BB3A5A408Q33292293-F48C919E-C459-4F68-BE7A-4423762E4698Q33295190-10C85F64-49DF-4E8C-B9C5-C6D2C33ACD45Q33848892-EA200103-BB4F-4129-8C2F-8671BE951851Q33943375-EC732DBF-BF48-4C17-B577-BF774EB2034FQ34165344-9361686D-45D1-4AC1-9840-9430A699B18EQ34245120-96BDD73B-DF79-4971-8F29-A5E1E4BA6703Q34455155-1A3B275B-6CF0-4F1D-8572-A098962C88DCQ35007632-6F7BE4A2-7C83-4B4B-A71C-D62D64705A22Q36439983-4653C9ED-DF71-4496-81A6-73470251688AQ36477430-73DAD1D6-D089-4DC0-A82D-54F54B9F363DQ37251921-36BFD15F-18D7-432F-BCC7-5D9656C7E72AQ37564942-778F2E18-EB44-4765-922A-A5C7AEA2FDAAQ37772151-060A8F49-8AE8-4E8A-BBA9-AC23FC9C66EEQ38652731-DE7A731D-50B9-400F-BA58-C39B9F5CC065Q38653290-661DCABB-090D-45C6-B47D-426E3068FC2BQ38788566-4942AC69-1850-42A8-A705-FFF5BCE6953FQ39004852-BB2B92F5-EE64-40B9-9DCA-02DAE0F2D05BQ39574311-AA5F7384-25B1-45C3-8F48-9F357F866716Q39747899-77319DF3-76B5-476F-8B52-A891B3CEEFDFQ39769430-F77CFFE6-80AE-4A64-BA3E-8D2EA2255B09Q39922435-3F3BF851-E394-433D-BD81-C864D6B24A86Q41040305-8F0F058D-35AA-407F-BF45-9A0A35704A32Q41861414-80CCF715-5199-45CE-935E-92541348D363Q41885754-A42BF141-56C6-4C2E-916C-AEA4FB74691DQ41897050-84105719-BC3A-40D6-A8E6-DCF9592E75F9Q41950182-BB347FA3-5E69-4B21-9311-C00B705320E3Q41995406-B1DBDCE2-00E8-4EAB-8F4E-17A9B092C219Q42240809-E004BA77-4E54-4CFC-9771-C87036F323D2Q42272239-8F81C16E-365B-478F-BF10-33A7AEB520DEQ42326400-39A23D3B-CAA5-4B1C-B4D4-611BBA259855Q42380787-407D0325-A08E-468C-862A-14A593283A93
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Martin M Knight
@ast
Martin M Knight
@en
Martin M Knight
@es
Martin M Knight
@nl
Martin M Knight
@sl
type
label
Martin M Knight
@ast
Martin M Knight
@en
Martin M Knight
@es
Martin M Knight
@nl
Martin M Knight
@sl
prefLabel
Martin M Knight
@ast
Martin M Knight
@en
Martin M Knight
@es
Martin M Knight
@nl
Martin M Knight
@sl
P106
P21
P31
P496
0000-0003-3755-1597