The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. - Wikidata - wikimedia - TriplyDB

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

http://www.wikidata.org/entity/Q42395973

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Replication-Associated Recombinational Repair: Lessons from Budding Yeast Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress Structural Insights into Ring Formation of Cohesin and Related Smc Complexes Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions DNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent Complexes Genetic instability in budding and fission yeast-sources and mechanisms The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stress Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids.The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth.Genome maintenance in Saccharomyces cerevisiae: the role of SUMO and SUMO-targeted ubiquitin ligases.The Smc5/Smc6/MAGE complex confers resistance to caffeine and genotoxic stress in Drosophila melanogaster.Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair.The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.ATPase-dependent control of the Mms21 SUMO ligase during DNA repair.Three Different Pathways Prevent Chromosome Segregation in the Presence of DNA Damage or Replication Stress in Budding Yeast Structure and function in the budding yeast nucleus.NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity Meiotic DNA joint molecule resolution depends on Nse5-Nse6 of the Smc5-Smc6 holocomplex SUMO: a multifaceted modifier of chromatin structure and function.DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes.Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells.The Nse2/Mms21 SUMO ligase of the Smc5/6 complex in the maintenance of genome stability.The Smc complexes in DNA damage response.Resolving complex chromosome structures during meiosis: versatile deployment of Smc5/6.Smc5/6 complex regulates Sgs1 recombination functions.Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci.The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains.Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.The Smc5/6 complex and the difficulties cutting the ties of twin sisters.Sgs1's roles in DNA end resection, HJ dissolution, and crossover suppression require a two-step SUMO regulation dependent on Smc5/6.Inhibition of the Smc5/6 complex during meiosis perturbs joint molecule formation and resolution without significantly changing crossover or non-crossover levels.The SMC5/6 complex is involved in crucial processes during human spermatogenesis.Scaffolding for Repair: Understanding Molecular Functions of the SMC5/6 Complex.PJA1 Coordinates with the SMC5/6 Complex to Restrict DNA Viruses and Episomal Genes through Interferon-independent Manner

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P2860

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

http://www.wikidata.org/entity/Q42395973

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

@zh-cn

name

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@en

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@nl

type

label

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@en

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@nl

prefLabel

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@en

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@nl

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Nucleic Acids Research

P1476

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

@en

P2093

Audrey Ceschia

http://www.w3.org/2001/XMLSchema#string

Giacomo de Piccoli

http://www.w3.org/2001/XMLSchema#string

Luis Aragón

http://www.w3.org/2001/XMLSchema#string

Neus Colomina

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P2860

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

SMC5 and MMS21 are required for chromosome cohesion and mitotic progression

Human MMS21/NSE2 is a SUMO ligase required for DNA repair

A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae

SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions.

A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization

Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks.

Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.

Cohesins: chromosomal proteins that prevent premature separation of sister chromatids

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6502-6512

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scholarly article

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10.1093/NAR/GKQ546

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19

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38

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Marcelino Bermúdez-López

Philippe Pasero

Jordi Torres-Rosell

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2010-06-22T00:00:00Z

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44695461

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20571088

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2965248

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