Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase (UNG) inhibitor development
about
Impact of linker strain and flexibility in the design of a fragment-based inhibitorStructure of uracil-DNA glycosylase fromMycobacterium tuberculosis: insights into interactions with ligandsUtilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase ‡Novel dimeric structure of phage 29-encoded protein p56: insights into uracil-DNA glycosylase inhibitionStructural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implicationsIdentification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasitesDirect screening of a dynamic combinatorial library using mass spectrometry.Mimicking damaged DNA with a small molecule inhibitor of human UNG2.Synthesis of a Homologous Series of Side Chain Extended Orthogonally-Protected Aminooxy-Containing Amino AcidsA rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH.Irreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesionDynamic combinatorial/covalent chemistry: a tool to read, generate and modulate the bioactivity of compounds and compound mixtures.Inhibition of DNA glycosylases via small molecule purine analogsEffect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase.Hydroxybenzaldoximes Are D-GAP-Competitive Inhibitors of E. coli 1-Deoxy-D-Xylulose-5-Phosphate SynthaseProtein p56 from the Bacillus subtilis phage phi29 inhibits DNA-binding ability of uracil-DNA glycosylase.Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA.Probing secondary interactions in biomolecular recognition by dynamic combinatorial chemistry.Timing facilitated site transfer of an enzyme on DNAOverexpression, purification, crystallization and preliminary X-ray analysis of uracil N-glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor.The catalytic power of uracil DNA glycosylase in the opening of thymine base pairs.Characterization of Bacillus subtilis uracil-DNA glycosylase and its inhibition by phage φ29 protein p56.A DNA array based on clickable lesion-containing hairpin probes for multiplexed detection of base excision repair activities.
P2860
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P2860
Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase (UNG) inhibitor development
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Uracil-directed ligand tetheri ...... se (UNG) inhibitor development
@en
Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase
@nl
type
label
Uracil-directed ligand tetheri ...... se (UNG) inhibitor development
@en
Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase
@nl
prefLabel
Uracil-directed ligand tetheri ...... se (UNG) inhibitor development
@en
Uracil-directed ligand tethering: an efficient strategy for uracil DNA glycosylase
@nl
P2093
P2860
P356
P1476
Uracil-directed ligand tetheri ...... se (UNG) inhibitor development
@en
P2093
Daniel J Krosky
James T Stivers
Lauren Seiple
Yu Lin Jiang
P2860
P304
17412-17420
P356
10.1021/JA055846N
P407
P577
2005-12-01T00:00:00Z