Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids. - Wikidata - wikimedia - TriplyDB

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

http://www.wikidata.org/entity/Q37288467

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P6981, An Arylstibonic Acid, Is a Novel Low Nanomolar Inhibitor of cAMP Response Element-Binding Protein Binding to DNA Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatch Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1 Diverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collection Arylstibonic acids: novel inhibitors and activators of human topoisomerase IB Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.Single cell trapping and DNA damage analysis using microwell arrays.Microscopic mechanism of DNA damage searching by hOGG1 Small molecule inhibitors of DNA repair nuclease activities of APE1.Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity.Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines Dichamanetin inhibits cancer cell growth by affecting ROS-related signaling components through mitochondrial-mediated apoptosis.Design and activity of AP endonuclease-1 inhibitors.Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigms Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neurons Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases.Base excision repair activities differ in human lung cancer cells and corresponding normal controls.Inhibition of Yersinia pestis DNA adenine methyltransferase in vitro by a stibonic acid compound: identification of a potential novel class of antimicrobial agents.Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors.Going ape as an approach to cancer therapeutics.Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells.Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.Human apurinic/apyrimidinic endonuclease 1.Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells.Molecular mechanisms of chemoresistance in osteosarcoma (Review).Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1.Receptor-based virtual screening and biological characterization of human apurinic/apyrimidinic endonuclease (Ape1) inhibitors.Essential role of DNA base excision repair on survival in an acidic tumor microenvironment.Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking.Efficient inhibition of human AP endonuclease 1 (APE1) via substrate masking by abasic site-binding macrocyclic ligands.Near-IR single fluorophore quenching system based on phthalocyanine (Pc) aggregation and its application for monitoring inhibitor/activator action on a therapeutic target: L1-EN

P2860

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P2860

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

http://www.wikidata.org/entity/Q37288467

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@en

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@nl

type

label

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@en

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@nl

prefLabel

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@en

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@nl

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P1433

Molecular Pharmacology

P1476

Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids.

@en

P2093

James T Stivers

http://www.w3.org/2001/XMLSchema#string

John H Cardellina

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Lauren A Seiple

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Rhone Akee

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P2860

Identification of redox/repair protein Ref-1 as a potent activator of p53

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme

Isolation of a small molecule inhibitor of DNA base excision repair.

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

Rate of depurination of native deoxyribonucleic acid

The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target

Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA

Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity.

Novel and specific inhibitors of a poxvirus type I topoisomerase.

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669-677

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scholarly article

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10.1124/MOL.107.042622

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3

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73

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2007-11-27T00:00:00Z

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5804636

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18042731

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2720577

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