Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.
about
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stressIn vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoformsChanges in protein structure and distribution observed at pre-clinical stages of scrapie pathogenesis.Heat shock proteins: cellular and molecular mechanisms in the central nervous system.Cytoplasmic prion protein induces forebrain neurotoxicityHsp40 couples with the CSPalpha chaperone complex upon induction of the heat shock response.Cell type-specific neuroprotective activity of untranslocated prion protein.A novel PrP partner HS-1 associated protein X-1 (HAX-1) protected the cultured cells against the challenge of H₂O₂.Reduction of PrP(C) in human cerebrospinal fluid after spinal cord injury.Development of kinomic analyses to identify dysregulated signaling pathways in cells expressing cytoplasmic PrP.Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation.Combined pharmacological induction of Hsp70 suppresses prion protein neurotoxicity in Drosophila.Prion protein biosynthesis and its emerging role in neurodegeneration.Prion protein at the crossroads of physiology and disease.The cellular prion protein (PrP(C)): its physiological function and role in diseaseMolecular basis of cerebral neurodegeneration in prion diseases.Neurotoxic species in prion disease: a role for PrP isoforms?Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection.The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases.The role of molecular chaperones in human misfolding diseases.Molecular pathology of human prion diseases.Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfoldingModeling general proteostasis: proteome balance in health and disease.Interaction between misfolded PrP and the ubiquitin-proteasome system in prion-mediated neurodegeneration.Protein misfolding in the late-onset neurodegenerative diseases: common themes and the unique case of amyotrophic lateral sclerosis.Prion disease: a tale of folds and strains.Dual role of cellular prion protein in normal host and Alzheimer's disease.Structural features within the nascent chain regulate alternative targeting of secretory proteins to mitochondria.Conserved stress-protective activity between prion protein and ShadooConditional modulation of membrane protein expression in cultured cells mediated by prion protein recognition of short phosphorothioate oligodeoxynucleotides.Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentationExploring prion protein biology in flies: genetics and beyond.Stress-protective signalling of prion protein is corrupted by scrapie prions.Pathogenic mutations in the glycosylphosphatidylinositol signal peptide of PrP modulate its topology in neuroblastoma cells.Shedding a negative image. Research into their mechanism of infectivity reveals that prions might have important biological rolesPrion protein lacks robust cytoprotective activity in cultured cells.The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins.Impaired transport of intrinsically disordered proteins through the Sec61 and SecY translocon; implications for prion diseases.
P2860
Q24309549-A148F5D8-8201-4139-B2FC-A05A1170A873Q28475550-A6411135-148D-4FAC-BDDD-7147A4BCD4ADQ30370633-480781CB-4A5D-4C27-8AD4-9611367B34B5Q30392284-02B77CBA-3A89-45B2-8DA9-D0C9F4B7A2EBQ30488090-5770E115-71FB-4C5F-8792-28FEF06D7DCBQ33412366-19D19EA2-E193-4EB2-BA8E-E6A4D99136F8Q33742065-87D28B01-2D97-4568-8637-AAAD107767CCQ33814409-FB9D6B0B-9258-45AA-81D6-3761D79CBBC4Q34102648-0FB5596B-9305-4D48-B96C-D4D2F6B209A9Q34812498-D66DF74C-526E-49DC-94D0-EF11EA478001Q35064216-90549937-5178-4F2D-A5A9-4248DF18489CQ35093650-1FB80F9D-83C1-43CE-8183-072F08DD5545Q35094535-303EE28D-0DF8-41B9-B9D2-62D90180E631Q35740063-1882CFFB-33F4-4608-8DC4-82FBE784607AQ36003019-FED3AB0A-2FB4-455F-87B6-2265BD7A404DQ36731464-36B4B231-E0A8-4CA4-B535-56E5E3D8FED5Q36974937-8B4E77ED-5F1E-4C6F-BDBB-B2BFE09835E7Q36981826-F482F723-2934-408A-8551-E1C9663FCD33Q37064056-A64B4227-372C-4973-BD41-7F52E1B39639Q37459598-667F1956-6858-4B27-8938-BABA65CD15FBQ37462236-A83E2DD0-CAF7-4F1B-8B73-B57C18A429CAQ37490746-659BEF5F-BAFB-46D7-9B63-59F8A2E0F832Q37815987-2AB5587C-0BE9-4C12-AAEE-519F83D6C31CQ38085466-122096DE-FE9D-43BE-AF2F-23DE814F6EDFQ38091029-BF1E2EB1-0D2A-48EB-BA57-E2F40C504215Q38099068-20591A86-CD44-44BC-9667-F605EC116F8AQ39245173-36F32C0D-CB7E-4B4D-AB77-9FB8FEEAF3F2Q39582237-4762B3ED-7B4B-470D-A2C0-6614C67C4560Q39604213-F5D60383-158A-423A-A15D-C02E1EDCAD1BQ39620231-A7207B2D-2678-46B4-929E-E7744AC16840Q39834753-373EEEA6-FAEA-4888-BC57-34D6DFE1A3D0Q39921558-77173026-01D1-43AC-AA06-81663780000DQ39970242-F106523A-F920-4083-96DA-F8F5B36941B5Q40004860-0D49EA7C-9D47-4858-9C42-149DBFF2AB8EQ42726280-0776D9EB-63E0-48FF-8EC6-C86865754118Q42745830-90E4FEB5-C1F3-4FA2-9A6E-04667801172EQ47586836-92992A7E-543A-4739-89FB-065CD4DE561EQ49501643-6AB4C488-7F48-4643-9C85-41100211C695
P2860
Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@en
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@nl
type
label
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@en
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@nl
prefLabel
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@en
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@nl
P2093
P2860
P50
P356
P1476
Association of Bcl-2 with misf ...... ic potential of cytosolic PrP.
@en
P2093
Angelika S Rambold
Margit Miesbauer
Michael Baier
Till Bartke
P2860
P304
P356
10.1091/MBC.E06-01-0083
P577
2006-05-17T00:00:00Z