Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation.
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Engineering liverStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewMultiscale models of cell signaling.Leveraging systems biology approaches in clinical pharmacologyTNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors.Models of signalling networks - what cell biologists can gain from them and give to themModeling the latent dimensions of multivariate signaling datasets.Bioreactor technologies to support liver function in vitro.The DIONESUS algorithm provides scalable and accurate reconstruction of dynamic phosphoproteomic networks to reveal new drug targets.Large-scale prediction and testing of drug activity on side-effect targets.Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein KinasesIn vitro models for liver toxicity testing.Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1?Addressing genetic tumor heterogeneity through computationally predictive combination therapy.Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches.Comparisons between in vitro whole cell imaging and in vivo zebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development.Latest advances in predicting DILI in human subjects: focus on biomarkers.Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.Next generation of network medicine: interdisciplinary signaling approaches.Optimized lysis buffer reagents for solubilization and preservation of proteins from cells and tissues.Metformin aggravates immune-mediated liver injury in mice.How Biophysical Forces Regulate Human B Cell Lymphomas.Dissecting the molecular pathophysiology of drug-induced liver injury.Systemic cytokine and chemokine responses in immunized mice challenged with staphylococcal enterotoxin B.
P2860
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P2860
Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@en
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@nl
type
label
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@en
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@nl
prefLabel
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@en
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@nl
P2093
P2860
P356
P1433
P1476
Cytokine-associated drug toxic ...... gnaling network dysregulation.
@en
P2093
Bart S Hendriks
Benjamin D Cosgrove
Leonidas G Alexopoulos
Linda G Griffith
Ta-chun Hang
P2860
P304
P356
10.1039/B926287C
P577
2010-04-01T00:00:00Z