Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation
about
Regulation of G protein-coupled receptors by allosteric ligandsAllosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's diseaseAllosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activationPreface.Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).Therapeutic potential of β-arrestin- and G protein-biased agonists.Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs.Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetrationEthylatropine Bromide as a Peripherally Restricted Muscarinic Antagonist.Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.
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P2860
Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
@zh-cn
name
Differential effects of allost ...... t, and receptor downregulation
@en
Differential effects of allost ...... t, and receptor downregulation
@nl
type
label
Differential effects of allost ...... t, and receptor downregulation
@en
Differential effects of allost ...... t, and receptor downregulation
@nl
prefLabel
Differential effects of allost ...... t, and receptor downregulation
@en
Differential effects of allost ...... t, and receptor downregulation
@nl
P2093
P2860
P356
P1476
Differential effects of allost ...... t, and receptor downregulation
@en
P2093
Albert A Davis
Allan I Levey
Ashley E Brady
Bonnie J Hanson
Craig J Heilman
James J Lah
Maya Fuerstenau-Sharp
Nicole R Miller
P2860
P304
P356
10.1021/CN100011E
P577
2010-08-01T00:00:00Z