22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.
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The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor proteinLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseApoE promotes the proteolytic degradation of AbetaLinking lipids, Alzheimer's and LXRs?Fetal Alcohol Spectrum Disorders: An Overview from the Glia PerspectiveOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseEthanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes.Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscleRetinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus.A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expressionOptimization of Rutaecarpine as ABCA1 Up-Regulator for Treating Atherosclerosis.Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway.Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 miceGlia and neurodevelopment: focus on fetal alcohol spectrum disorders.Cholesterol: from heart attacks to Alzheimer's disease.Cholesterol metabolism and homeostasis in the brainProtein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages.RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's DiseaseA-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration.Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors.Novel advances in shotgun lipidomics for biology and medicine.Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.ABC Transporters and the Alzheimer's Disease Enigma.ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux.microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the BrainLiver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient miceAnalysis of bioactive oxysterols in newborn mouse brain by LC/MS.Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.Expression profiling in APP23 mouse brain: inhibition of Abeta amyloidosis and inflammation in response to LXR agonist treatmentRole of ABC transporters in the pathogenesis of Alzheimer's diseaseCholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis.Oxysterols and Alzheimer's disease.Prenatal Ethanol Exposure Up-Regulates the Cholesterol Transporters ATP-Binding Cassette A1 and G1 and Reduces Cholesterol Levels in the Developing Rat Brain.Oxysterols, cholesterol homeostasis, and Alzheimer disease.Cholesterol homeostasis in the developing brain: a possible new target for ethanol.Role of ATP-binding cassette transporters in brain lipid transport and neurological disease.
P2860
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P2860
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@en
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@nl
type
label
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@en
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@nl
prefLabel
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@en
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@nl
P2093
P356
P1476
22R-hydroxycholesterol and 9-c ...... crease amyloid beta secretion.
@en
P2093
Barbara A Isanski
Iliya M Lefterov
John Skoko
Milos D Ikonomovic
Preslav I Lefterov
Steven T DeKosky
P304
13244-13256
P356
10.1074/JBC.M300044200
P407
P577
2003-01-22T00:00:00Z