Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.
about
A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylationIon Channels in the HeartIn-Depth Study of the Interaction, Sensitivity, and Gating Modulation by PUFAs on K+ Channels; Interaction and New TargetsSimulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validationDeterminants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysisA compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytesComprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependenceK+ channel KVLQT1 located in the basolateral membrane of distal colonic epithelium is not essential for activating Cl- secretionInherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels.Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential.Cardiac adrenergic control and atrial fibrillation.A Carbohydrate Fraction, AIP1, from Artemisia Iwayomogi Reduces the Action Potential Duration by Activation of Rapidly Activating Delayed Rectifier K Channels in Rabbit Ventricular MyocytesBeta-adrenergic stimulation reverses the I Kr-I Ks dominant pattern during cardiac action potentialIKs protects from ventricular arrhythmia during cardiac ischemia and reperfusion in rabbits by preserving the repolarization reserve.Autonomic nerve stimulation reverses ventricular repolarization sequence in rabbit heartsLocal control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient.Cardiac ventricular repolarization reserve: a principle for understanding drug-related proarrhythmic risk.The acute inotropic effects of cardiac contractility modulation (CCM) are associated with action potential duration shortening and mediated by β1-adrenoceptor signalling.Gender differences in the slow delayed (IKs) but not in inward (IK1) rectifier K+ currents of canine Purkinje fibre cardiac action potential: key roles for IKs, beta-adrenoceptor stimulation, pacing rate and gender.Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserveModelling and imaging cardiac repolarization abnormalities.Quantitative comparison of cardiac ventricular myocyte electrophysiology and response to drugs in human and nonhuman species.Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Computational biology in the study of cardiac ion channels and cell electrophysiology.Double pharmacological challenge on repolarization opens new avenues for drug safety research.Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes.The plateau outward current in canine ventricle, sensitive to 4-aminopyridine, is a constitutive contributor to ventricular repolarizationAntiarrhythmic action of beta-blockers: potential mechanisms.Role of action potential configuration and the contribution of C²⁺a and K⁺ currents to isoprenaline-induced changes in canine ventricular cells.Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulationGenotype- and Sex-Specific QT-RR Relationship in the Type-1 Long-QT Syndrome.Single-channel basis for the slow activation of the repolarizing cardiac potassium current, I(Ks)Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbitsAdrenaline reveals the torsadogenic effect of combined blockade of potassium channels in anaesthetized guinea pigs.New cell models and assays in cardiac safety profiling.Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserveAntibodies with beta-adrenergic activity from chronic chagasic patients modulate the QT interval and M cell action potential duration.Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium.Modulation of KCNQ1 alternative splicing regulates cardiac IKs and action potential repolarization.Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis
P2860
Q24309447-42FA35DA-D365-40F2-8DB9-02FB7D90D328Q26829681-01776B64-054A-4595-88BE-D29EA9129D20Q28066803-2B932E13-CF20-4758-8FE4-9575104B4028Q28478313-E56AE22E-B19A-4EE9-8DFC-D91B32D169C5Q28535491-BA45F48E-AAB5-4B20-9FCA-642F6255CB1CQ28540046-6AC62308-0EF0-485A-94BF-7017DACBC2D1Q28541597-EF8250B6-00E2-428D-B2E0-40739D67BFD4Q28583510-E55B2346-30C8-420B-9052-A2D4B9DE3DC0Q33152183-4F488198-34CF-4710-A5EE-0AEF89E98678Q33661043-9C296713-CC8E-4F29-A0EA-79E70C6A1BB5Q33792556-F26CE846-6341-448B-8E0E-F7AF8D2359D0Q33988326-5D9AC8D5-7FBF-4D12-AA7E-FB45CC3CD5C5Q34067125-0916FE4A-9F4A-49A4-BD52-90ED3D85335BQ34181761-715F2B55-DFAE-47F5-AC02-C0D829B3B54DQ34493218-BDD54B49-041F-445E-B6E6-8303C4A2FFA6Q34785976-06380D70-9B14-4080-9C42-492933C13CE5Q35210010-30AC15D4-3820-408C-81A1-2CD26785AE97Q35223644-1D72D7A7-D42D-4327-8FE2-7399DE3028F7Q35545348-81BB8A5D-3ABD-44FA-AC05-229B39530CACQ35676902-3E6ECF59-2B86-4A8F-8B09-638C34C21E40Q35783131-1DFD4A4D-2960-4A93-8CD5-73BA4DC974C1Q35850064-A2BF8893-6426-45E2-982A-C6D8D0411C7FQ35893721-E0538442-C088-443D-881F-E8E836C2BDB4Q36015209-B3517AAF-D673-457C-BAED-8A4E02498EA6Q36094270-538B495B-BE26-4A68-B2D6-40C45ED1365AQ36094299-5D81F43E-AF97-455D-A4CB-7921341F157AQ36144683-4A6FF3BF-3F81-4968-A0DC-43AD6B01B942Q36167672-B782E74F-41AD-4C90-ADED-265DDBB83D5FQ36254025-6BE39899-A9D3-49BF-B1DD-CB9848995446Q36358654-158CA3B7-FCEB-4788-A830-4F589D11EE9EQ36366350-BB06E67E-F9A3-4F63-A248-3D290AAB6C88Q36692993-BAB4A2E7-43CC-461B-AEB1-4B67A6C0AF06Q36791351-390020A4-EE9F-4C06-A700-8B7F67231367Q36801845-742BA535-F84E-41EF-98E5-E25BDF5EF35CQ36909315-D4F59BC4-563F-479C-912C-A53D4681EA66Q36943422-E68AC875-89DD-45B4-A2AA-80BE83DC6CF7Q37152049-ACA9C7E8-32E6-4753-9760-9E3FDA7170C3Q37162572-AC74745C-B258-4B2B-86C4-9BF597CE7E63Q37166829-A571C676-4261-4336-A729-361E04EC1BDDQ37263480-30DE3601-4616-42E3-8811-5C8E5A077887
P2860
Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Probing the contribution of IK ...... renergic receptor stimulation.
@en
Probing the contribution of IK ...... renergic receptor stimulation.
@nl
type
label
Probing the contribution of IK ...... renergic receptor stimulation.
@en
Probing the contribution of IK ...... renergic receptor stimulation.
@nl
prefLabel
Probing the contribution of IK ...... renergic receptor stimulation.
@en
Probing the contribution of IK ...... renergic receptor stimulation.
@nl
P2093
P1433
P1476
Probing the contribution of IK ...... drenergic receptor stimulation
@en
P2093
Jet D M Beekman
Jurren M van Opstal
Karin R Sipido
Marc A Vos
Paul G A Volders
Uwe Gerlach
P304
P356
10.1161/01.CIR.0000068344.54010.B3
P407
P577
2003-05-19T00:00:00Z