Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil.
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Mechanism-based design of 2,3-benzodiazepine inhibitors for AMPA receptorsFunctional implications of axon initial segment cytoskeletal disruption in strokeMolecular programs induced by heat acclimation confer neuroprotection against TBI and hypoxic insults via cross-tolerance mechanismsPICK1-mediated glutamate receptor subunit 2 (GluR2) trafficking contributes to cell death in oxygen/glucose-deprived hippocampal neuronsDelayed neuronal cell death in brainstem after transient brainstem ischemia in gerbils.Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced deathIschemic preconditioning acts upstream of GluR2 down-regulation to afford neuroprotection in the hippocampal CA1Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction.Evidence for low GluR2 AMPA receptor subunit expression at synapses in the rat basolateral amygdala.Nuclear respiratory factor 2 regulates the transcription of AMPA receptor subunit GluA2 (Gria2)NR2B-NMDA receptor-mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signalingInhibiting PTEN protects hippocampal neurons against stretch injury by decreasing membrane translocation of AMPA receptor GluR2 subunit.Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia.Gestational nicotine exposure regulates expression of AMPA and NMDA receptors and their signaling apparatus in developing and adult rat hippocampus.Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal deathExposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing.Oxygen/glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptorsRedox regulation of intracellular zinc: molecular signaling in the life and death of neuronsIn vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons.Estradiol pretreatment ameliorates impaired synaptic plasticity at synapses of insulted CA1 neurons after transient global ischemia.Rapid glutamate receptor 2 trafficking during retinal degeneration.The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brainAstrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.TNF-α triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury.Epigenetic mechanisms in stroke and epilepsy.Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemiaGlutamate receptor plasticity and activity-regulated cytoskeletal associated protein regulation in the phrenic motor nucleus may mediate spontaneous recovery of the hemidiaphragm following chronic cervical spinal cord injury.Ionotropic glutamate receptors & CNS disorders.Remodeling of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit composition in hippocampal neurons after global ischemiaTranslational regulation of GluR2 mRNAs in rat hippocampus by alternative 3' untranslated regions.The crossed phrenic phenomenon and recovery of function following spinal cord injury.Therapeutic targets for neuroprotection in acute ischemic stroke: lost in translation?Ca permeable AMPA channels in diseases of the nervous system.Excitotoxicity through Ca2+-permeable AMPA receptors requires Ca2+-dependent JNK activation.Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo.Distinct subunit-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking mechanisms in cultured cortical and hippocampal neurons in response to oxygen and glucose deprivation.The protective effect of heat acclimation from hypoxic damage in the brain involves changes in the expression of glutamate receptors.Endocytosis and lysosomal degradation of GluA2/3 AMPARs in response to oxygen/glucose deprivation in hippocampal but not cortical neurons.Insights into the cellular and molecular contributions of MeCP2 overexpression to disease pathophysiology.Lesion-induced enhancement of LTP in rat visual cortex is mediated by NMDA receptors containing the NR2B subunit.
P2860
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P2860
Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@en
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@nl
type
label
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@en
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@nl
prefLabel
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@en
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@nl
P2093
P1476
Global ischemia induces downre ...... ocampal CA1 neurons of gerbil.
@en
P2093
D M Rosenbaum
E M Aronica
J A Connor
J A Gorter
J J Petrozzino
M V Bennett
P304
P356
10.1523/JNEUROSCI.17-16-06179.1997
P407
P577
1997-08-01T00:00:00Z