Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.
about
Cardiac regulation by phosphoinositide 3-kinases and PTENBeta-adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKAPhosphoinositides: tiny lipids with giant impact on cell regulationPI3Kγ in hypertension: a novel therapeutic target controlling vascular myogenic tone and target organ damageThe Multifaceted Roles of PI3Kγ in Hypertension, Vascular Biology, and InflammationCurcumin alleviates diabetic cardiomyopathy in experimental diabetic ratsCpG-ODN attenuates pathological cardiac hypertrophy and heart failure by activation of PI3Kα-Akt signalingCardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in miceInsulin Signaling and Heart Failure.Genetics of hypertension: discoveries from the bench to human populations.Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs)PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway.Protective Role for LPA3 in Cardiac Hypertrophy Induced by Myocardial Infarction but Not by Isoproterenol.Distinct functions of junD in cardiac hypertrophy and heart failureRapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.β-Adrenergic receptor-PI3K signaling crosstalk in mouse heart: elucidation of immediate downstream signaling cascades.PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy.The coordinated increased expression of biliverdin reductase and heme oxygenase-2 promotes cardiomyocyte survival: a reductase-based peptide counters β-adrenergic receptor ligand-mediated cardiac dysfunction.Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.Carvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII.Cardiac phenotype induced by a dysfunctional α 1C transgene: a general problem for the transgenic approachFeedback mechanisms for cardiac-specific microRNAs and cAMP signaling in electrical remodeling.Cancer Therapy Targeting the HER2-PI3K Pathway: Potential Impact on the Heart.Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways.Insulin-like growth factor 1 prevents diastolic and systolic dysfunction associated with cardiomyopathy and preserves adrenergic sensitivityPhosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes.Insulin signaling pathways and cardiac growth.Role of phosphoinositide 3-kinase IA (PI3K-IA) activation in cardioprotection induced by ouabain preconditioningTripartite motif 32 prevents pathological cardiac hypertrophyFlavonoids Extraction from Propolis Attenuates Pathological Cardiac Hypertrophy through PI3K/AKT Signaling Pathway.Myocardial AKT: the omnipresent nexus.Surgical ventricular reconstruction in mice: elucidating potential targets for combined molecular/surgical intervention.Ginsenoside rb1 reduces isoproterenol-induced cardiomyocytes apoptosis in vitro and in vivo.Taking the heart failure battle inside the cell: small molecule targeting of Gβγ subunitsCardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes.Phosphoinositide-3 kinase signaling in cardiac hypertrophy and heart failureRegulation of β-adrenergic receptor function: an emphasis on receptor resensitization.Rodent models of heart failure: an updated review.Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy.
P2860
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P2860
Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Phosphoinositide 3-kinase gamm ...... terenol-induced heart failure.
@en
Phosphoinositide 3-kinase gamm ...... terenol-induced heart failure.
@nl
type
label
Phosphoinositide 3-kinase gamm ...... terenol-induced heart failure.
@en
Phosphoinositide 3-kinase gamm ...... terenol-induced heart failure.
@nl
prefLabel
Phosphoinositide 3-kinase gamm ...... terenol-induced heart failure.
@en
Phosphoinositide 3-kinase gamm ...... terenol-induced heart failure.
@nl
P2093
P50
P1433
P1476
Phosphoinositide 3-kinase gamm ...... oterenol-induced heart failure
@en
P2093
Dominica Gidrewicz
Gavin Y Oudit
Ivona Kozieradzki
Junko Irie-Sasaki
Michael A Crackower
Peter H Backx
Renu Sarao
Susan F Steinberg
Teiji Wada
Vitalyi O Rybin
P304
P356
10.1161/01.CIR.0000091403.62293.2B
P407
P577
2003-09-08T00:00:00Z