about
DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxisCaspase-3 regulates cell cycle in B cells: a consequence of substrate specificityThe ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells3' Phosphatase activity toward phosphatidylinositol 3,4-bisphosphate [PI(3,4)P2] by voltage-sensing phosphatase (VSP)Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.Essential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cellsPortrait of PTEN: messages from mutant mice.Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia.The pathophysiological roles of PI3Ks and therapeutic potential of selective inhibitors in allergic inflammation.Phosphatidylinositol-3,5-bisphosphate: metabolism and physiological functions.Diet-induced macrophage inhibitory cytokine 1 promotes prostate cancer progression.Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.Critical roles of the p110 beta subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells.IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts.The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells.JNK-interacting protein 1 promotes Akt1 activation.Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling.Phospholipase D2 functions as a downstream signaling molecule of MAP kinase pathway in L1-stimulated neurite outgrowth of cerebellar granule neurons.MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence.Involvement of proton-sensing TDAG8 in extracellular acidification-induced inhibition of proinflammatory cytokine production in peritoneal macrophages.CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.Essential role for phospholipase D2 activation downstream of ERK MAP kinase in nerve growth factor-stimulated neurite outgrowth from PC12 cells.TMEM55a localizes to macrophage phagosomes to down-regulate phagocytosis.Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production.Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells.Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.[Phosphoinositides in membrane traffic].PI(3)Kγ has an important context-dependent role in neutrophil chemokinesisRegulation of Fc R-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3 mediated phagocytosis by differential recruitment of these 5-phosphatases to the pKeratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formationInteraction between telencephalin and ERM family proteins mediates dendritic filopodia formationDynamics of human erythroblast enucleation[Role of PTEN tumor suppressor gene in disease: PTEN-deficient mice]Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiencyA Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites
P50
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P50
description
researcher
@en
name
Takehiko Sasaki
@en
Takehiko Sasaki
@nl
type
label
Takehiko Sasaki
@en
Takehiko Sasaki
@nl
prefLabel
Takehiko Sasaki
@en
Takehiko Sasaki
@nl
P106
P31
P496
0000-0003-1837-3748