High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors.
about
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancersProteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancerAssociation of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancerThe rebel angel: mutant p53 as the driving oncogene in breast cancer.SF3B1 mutations constitute a novel therapeutic target in breast cancer.BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays.Tumorigenic WAP-T mouse mammary carcinoma cells: a model for a self-reproducing homeostatic cancer cell system.Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancersAssociation between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancerEstrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic featuresElafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics.BRCA1 pathway function in basal-like breast cancer cells.Immunophenotypic predictive profiling of BRCA1-associated breast cancer.BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability.Stem cell-like gene expression in ovarian cancer predicts type II subtype and prognosisTTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer.Metformin and erlotinib synergize to inhibit basal breast cancer.The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expressionTP53 status and response to treatment in breast cancersCyclophosphamide dose intensification may circumvent anthracycline resistance of p53 mutant breast cancers.High frequency of complex TP53 mutations in CNS metastases from breast cancer.Genetic characterization of breast cancer and implications for clinical managementLevels of DNA Methylation Vary at CpG Sites across the BRCA1 Promoter, and Differ According to Triple Negative and "BRCA-Like" Status, in Both Blood and Tumour DNA.Nonsynonymous Single-Nucleotide Variations on Some Posttranslational Modifications of Human Proteins and the Association with DiseasesFirst description of a sporadic breast cancer in a woman with BRCA1 germline mutation.Breast cancer phenotype in women with TP53 germline mutations: a Li-Fraumeni syndrome consortium effort.A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.Biomarkers for Basal-like Breast Cancer.The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.Preclinical mouse models for BRCA1-associated breast cancer.Long-term survival of advanced triple-negative breast cancers with a dose-intense cyclophosphamide/anthracycline neoadjuvant regimen.Histological types of breast cancer: how special are they?Beyond triple-negative breast cancer: the need to define new subtypes.Studying therapy response and resistance in mouse models for BRCA1-deficient breast cancer.Phenotype-genotype correlation in familial breast cancer.Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.Triple-negative breast cancer: new perspectives for novel therapies.
P2860
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P2860
High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@en
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@nl
type
label
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@en
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@nl
prefLabel
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@en
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@nl
P2093
P50
P1433
P1476
High frequency of TP53 mutatio ...... n BRCA1 luminal breast tumors.
@en
P2093
Audrey Remenieras
Elisabeth Turpin
Elodie Manié
Gaelle Pierron
Ingrid Lebigot
Jacqueline Lehmann-Che
Jean Feunteun
Mathilde Warcoin
Nadège Gruel
Rosette Lidereau
P304
P356
10.1158/0008-5472.CAN-08-1560
P407
P50
P577
2009-01-01T00:00:00Z