Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation. - Wikidata - wikimedia - TriplyDB

Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation.

Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation.

http://www.wikidata.org/entity/Q42453573

about

PKCδ stabilizes TAp63 to promote cell apoptosis Molecular characterization of thyroid toxicity: anchoring gene expression profiles to biochemical and pathologic end points.The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System Regulation of p63 protein stability via ubiquitin-proteasome pathway.Gadd45 proteins: relevance to aging, longevity and age-related pathologies.ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT Gadd45a functions as a promoter or suppressor of breast cancer dependent on the oncogenic stress UVB radiation-induced β-catenin signaling is enhanced by COX-2 expression in keratinocytes Ultraviolet radiation and skin cancer: molecular mechanisms.MiR-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45α.Gadd45a inhibits cell migration and invasion by altering the global RNA expression.Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury.Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway.Circulatory shear flow alters the viability and proliferation of circulating colon cancer cells Non-classical p38 map kinase functions: cell cycle checkpoints and survival.Oral lichen planus and the p53 family: what do we know?Response of the adipose tissue transcriptome to dihydrotestosterone in mice.Molecular determinants of Akt-induced keratinocyte transformation.JNK1 inhibits transcriptional and pro-apoptotic activity of TAp63γ.Decreased expression of p63 in oral lichen planus and graft-vs.-host disease associated with oral inflammation.Oxidative stress-induced Gadd45α inhibits trophoblast invasion and increases sFlt1/sEng secretions via p38 MAPK involving in the pathology of pre-eclampsia.Gadd45a regulates beta-catenin distribution and maintains cell-cell adhesion/contact.

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Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation.

http://www.wikidata.org/entity/Q42453573

description

2004 nî lūn-bûn

@nan

2004年の論文

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2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

2004年论文

@zh

2004年论文

@zh-cn

name

Gadd45a regulates matrix metal ...... se and APC complex activation.

@en

Gadd45a regulates matrix metal ...... se and APC complex activation.

@nl

type

label

Gadd45a regulates matrix metal ...... se and APC complex activation.

@en

Gadd45a regulates matrix metal ...... se and APC complex activation.

@nl

prefLabel

Gadd45a regulates matrix metal ...... se and APC complex activation.

@en

Gadd45a regulates matrix metal ...... se and APC complex activation.

@nl

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Gadd45a regulates matrix metal ...... se and APC complex activation.

@en

P2093

Galina I Belova

http://www.w3.org/2001/XMLSchema#string

Jeffrey Hildesheim

http://www.w3.org/2001/XMLSchema#string

Lilit Vardanian

http://www.w3.org/2001/XMLSchema#string

Stuart D Tyner

http://www.w3.org/2001/XMLSchema#string

Xiwu Zhou

http://www.w3.org/2001/XMLSchema#string

P2860

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

beta-catenin signaling and cancer

Matrix metalloproteinases: multifunctional contributors to tumor progression

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

p63 is a p53 homologue required for limb and epidermal morphogenesis

Live or let die: the cell's response to p53

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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P304

1829-1837

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scholarly article

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10.1038/SJ.ONC.1207301

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10

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23

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Albert J Fornace

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2004-03-01T00:00:00Z

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8984245

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1045669858

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14647429

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