Molecular determinants of Akt-induced keratinocyte transformation.
about
The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signalingPim-2 phosphorylation of p21(Cip1/WAF1) enhances its stability and inhibits cell proliferation in HCT116 cellsUVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytesSensing and integration of Erk and PI3K signals by MycRapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.Establishment of a murine epidermal cell line suitable for in vitro and in vivo skin modellingPhloroglucinol induces apoptosis through the regulation of insulin-like growth factor 1 receptor signaling pathways in human colon cancer HT-29 cells.Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinomaThe PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Biomarkers of epithelial-mesenchymal transition in squamous cell carcinoma.Novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets.Defining the origins of Ras/p53-mediated squamous cell carcinomaThe thyroid hormone receptors as modulators of skin proliferation and inflammationPIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitroEmerging drugs to treat squamous cell carcinomas of the head and neck.Application of a Persistent Heparin Treatment Inhibits the Malignant Potential of Oral Squamous Carcinoma Cells Induced by Tumor Cell-Derived Exosomes.EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications.EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapyArsenic trioxide-induced growth arrest of breast cancer MCF-7 cells involving FOXO3a and IκB kinase β expression and localization.Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signalingThe PTEN-Akt pathway impacts the integrity and composition of mitotic centrosomesRegulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cellsCarboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylationRequirement for metalloproteinase-dependent ERK and AKT activation in UVB-induced G1-S cell cycle progression of human keratinocytes.Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development.Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis.AKT in cancer: new molecular insights and advances in drug development.ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization.Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinomaCurcumin inhibits skin squamous cell carcinoma tumor growth in vivo.Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells.An adult passive transfer mouse model to study desmoglein 3 signaling in pemphigus vulgaris.Transgenic mice expressing constitutively active Akt in oral epithelium validate KLFA as a potential biomarker of head and neck squamous cell carcinoma.Akt signaling leads to stem cell activation and promotes tumor development in epidermis.Unique roles of estrogen-dependent Pten control in epithelial cell homeostasis of mouse vagina.Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.Lycopene Protects Keratinocytes Against UVB Radiation-Induced Carcinogenesis via Negative Regulation of FOXO3a Through the mTORC2/AKT Signaling Pathway.
P2860
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P2860
Molecular determinants of Akt-induced keratinocyte transformation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Molecular determinants of Akt-induced keratinocyte transformation.
@en
Molecular determinants of Akt-induced keratinocyte transformation.
@nl
type
label
Molecular determinants of Akt-induced keratinocyte transformation.
@en
Molecular determinants of Akt-induced keratinocyte transformation.
@nl
prefLabel
Molecular determinants of Akt-induced keratinocyte transformation.
@en
Molecular determinants of Akt-induced keratinocyte transformation.
@nl
P2093
P2860
P356
P1433
P1476
Molecular determinants of Akt-induced keratinocyte transformation.
@en
P2093
A B Martínez-Cruz
C Ballestín
C Segrelles
J Martínez-Palacio
M Fernanda Lara
P Hernández
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209155
P407
P577
2006-02-01T00:00:00Z
P5875
P6179
1036740690