Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.
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Type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularisStructure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenaseCrystal Structures of Three Classes of Non-Steroidal Anti-Inflammatory Drugs in Complex with Aldo-Keto Reductase 1C3Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate CancerConversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERINGStructure of AKR1C3 with 3-phenoxybenzoic acid boundStructures of complexes of type 5 17β-hydroxysteroid dehydrogenase with structurally diverse inhibitors: insights into the conformational changes upon inhibitor bindingSpecies used for drug testing reveal different inhibition susceptibility for 17beta-hydroxysteroid dehydrogenase type 1Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkeyCharacterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency.The dilemma of the gender assignment in a Portuguese adolescent with disorder of sex development due to 17β-hydroxysteroid-dehydrogenase type 3 enzyme deficiencyInhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3): overview and structural insights.Phenotypic variability in 17beta-hydroxysteroid dehydrogenase-3 deficiency and diagnostic pitfalls.Non steroidal anti-inflammatory drug use and levels of oestrogens and androgens in men.Promiscuity and diversity in 3-ketosteroid reductases.Severe Undervirilisation in a 46,XY Case Due to a Novel Mutation in HSD17B3 GeneCurrent physico-biochemistry in steroid research and status of structural biology for steroid-converting enzymes.Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism.Characterization of hamster NAD+-dependent 3(17)β-hydroxysteroid dehydrogenase belonging to the aldo-keto reductase 1C subfamily.
P2860
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P2860
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Crystal structures of the mult ...... n in human peripheral tissues.
@en
Crystal structures of the mult ...... n in human peripheral tissues.
@nl
type
label
Crystal structures of the mult ...... n in human peripheral tissues.
@en
Crystal structures of the mult ...... n in human peripheral tissues.
@nl
prefLabel
Crystal structures of the mult ...... n in human peripheral tissues.
@en
Crystal structures of the mult ...... n in human peripheral tissues.
@nl
P2093
P356
P1476
Crystal structures of the mult ...... n in human peripheral tissues.
@en
P2093
Fernand Labrie
P304
P356
10.1210/ME.2004-0032
P577
2004-04-15T00:00:00Z