Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
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Essential role of retinoblastoma protein in mammalian hair cell development and hearing.Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cellsPrestin and the cochlear amplifierHigh frequency of the IVS2-2A>G DNA sequence variation in SLC26A5, encoding the cochlear motor protein prestin, precludes its involvement in hereditary hearing loss.Genetics of hearing and deafnessHearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrinSusceptibility of outer hair cells to cholesterol chelator 2-hydroxypropyl-β-cyclodextrine is prestin-dependentPrestin-Dependence of Outer Hair Cell Survival and Partial Rescue of Outer Hair Cell Loss in PrestinV499G/Y501H Knockin MiceLong-term administration of salicylate enhances prestin expression in rat cochleaThe hearing gene Prestin reunites echolocating bats.Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins.Auditory hair cell-specific deletion of p27Kip1 in postnatal mice promotes cell-autonomous generation of new hair cells and normal hearing.Reduction in noise-induced functional loss of the cochleae in mice with pre-existing cochlear dysfunction due to genetic interference of prestin.Developmental expression of the outer hair cell motor prestin in the mouseOuter hair cell-specific prestin-CreERT2 knockin mouse lines.Normal hearing sensitivity at low-to-middle frequencies with 34% prestin-charge densitySomatic motility and hair bundle mechanics, are both necessary for cochlear amplification?Using the cochlear microphonic as a tool to evaluate cochlear function in mouse models of hearing.Deficient forward transduction and enhanced reverse transduction in the alpha tectorin C1509G human hearing loss mutation.Prestin-based outer hair cell electromotility in knockin mice does not appear to adjust the operating point of a cilia-based amplifier.In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal micePrestin-based outer hair cell motility is necessary for mammalian cochlear amplification.A chimera analysis of prestin knock-out miceCochlear amplification, outer hair cells and prestin.Interaction between the motor protein prestin and the transporter protein VAPAOtoacoustic emissions without somatic motility: can stereocilia mechanics drive the mammalian cochlea?Identifying components of the hair-cell interactome involved in cochlear amplificationVacuolization and alterations of lysosomal membrane proteins in cochlear marginal cells contribute to hearing loss in neuraminidase 1-deficient miceCell cycle regulation in hair cell development and regeneration in the mouse cochlea.The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer.Slc26a9 is inhibited by the R-region of the cystic fibrosis transmembrane conductance regulator via the STAS domain.Glucose transporter 5 is undetectable in outer hair cells and does not contribute to cochlear amplification.The R130S mutation significantly affects the function of prestin, the outer hair cell motor protein.Abnormal mRNA splicing but normal auditory brainstem response (ABR) in mice with the prestin (SLC26A5) IVS2-2A>G mutation.Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner EarThe auditory phenotype of children harboring mutations in the prestin gene.CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.Prestin shows divergent evolution between constant frequency echolocating bats.Loss of the Cochlear Amplifier Prestin Reduces Temporal Processing Efficacy in the Central Auditory System
P2860
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P2860
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@en
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@nl
type
label
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@en
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@nl
prefLabel
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@en
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@nl
P2093
P1476
Hearing threshold elevation precedes hair-cell loss in prestin knockout mice.
@en
P2093
Jiangang Gao
Yunkai Guo
P356
10.1016/J.MOLBRAINRES.2004.03.020
P577
2004-07-01T00:00:00Z