Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease.
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Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung diseaseTargeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunitiesOxidation increases mucin polymer cross-links to stiffen airway mucus gelsAirway mucus function and dysfunction.EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 productionEpidermal growth factor receptor activity is necessary for mouse basal cell proliferationUpdate in chronic obstructive pulmonary disease in 2010.The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.Cell counting in human endobronchial biopsies--disagreement of 2D versus 3D morphometry.Novel outcomes and end points: biomarkers in chronic obstructive pulmonary disease clinical trialsBRET Biosensor Analysis of Receptor Tyrosine Kinase Functionality.DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma.Chronic obstructive pulmonary disease and lung cancer: new molecular insights.Cellular and molecular mechanisms of goblet cell metaplasia in the respiratory airways.New anti-inflammatory targets for chronic obstructive pulmonary disease.Targeting mucus hypersecretion: new therapeutic opportunities for COPD?Emerging pharmaceutical therapies for COPD.Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.Inhaled tyrosine kinase inhibitors for pulmonary hypertension: a possible future treatment.Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model.EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-Induced Lesions in the Human Airway Epithelium.Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFRMore Than Meets the Eye: Cigarette Smoke Induces Genomic Changes in the Small Airway Epithelium Independent of Histologic Changes.New targets for resolution of airway remodeling in obstructive lung diseases.A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells
P2860
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P2860
Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
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name
Safety and efficacy of an inha ...... obstructive pulmonary disease.
@en
Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor
@nl
type
label
Safety and efficacy of an inha ...... obstructive pulmonary disease.
@en
Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor
@nl
prefLabel
Safety and efficacy of an inha ...... obstructive pulmonary disease.
@en
Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor
@nl
P2093
P2860
P1476
Safety and efficacy of an inha ...... obstructive pulmonary disease.
@en
P2093
Antje Prasse
E Rand Sutherland
Gerard J Criner
John V Fahy
Kay Tetzlaff
Mark T Dransfield
Michael C Nivens
Michael Wolff
Norbert Krug
Prescott G Woodruff
P2860
P304
P356
10.1164/RCCM.200909-1415OC
P407
P577
2009-12-10T00:00:00Z