Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice.
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Unique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CARDifferential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skinAP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermisEsophageal Cancer: Insights From Mouse ModelsThe lac operator-repressor system is functional in the mouseRoles for β-catenin and doxycycline in the regulation of respiratory epithelial cell frequency and functionAn Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic MiceCo-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cellsPeptide aptamers: recent developments for cancer therapy.pTcINDEX: a stable tetracycline-regulated expression vector for Trypanosoma cruzi.Wounding the cornea to learn how it heals.TGF-alpha increases astrocyte invasion and promotes axonal growth into the lesion following spinal cord injury in mice.Dual inhibition of both the epidermal growth factor receptor and erbB2 effectively inhibits the promotion of skin tumors during two-stage carcinogenesis.Local microenvironment provides important cues for cell differentiation in lingual epithelia.Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.Keratinocyte-targeted expression of human laminin γ2 rescues skin blistering and early lethality of laminin γ2 deficient mice.KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia.The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisDisrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development.Targeting the function of the HER2 oncogene in human cancer therapeutics.β-catenin dosage is a critical determinant of tracheal basal cell fate determination.Review: Experimental models for Barrett's esophagus and esophageal adenocarcinomaErbb2 regulates inflammation and proliferation in the skin after ultraviolet irradiationDevelopment of an inducible gene expression system for primary murine keratinocytesBeyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology.Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies.Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissuesThe a"MAZE"ing world of lung-specific transgenic mice.The role of HER2 in early breast cancer metastasis and the origins of resistance to HER2-targeted therapies.Caveolin-1 and altered neuregulin signaling contribute to the pathophysiological progression of diabetic peripheral neuropathy.Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesisDevelopmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells.Genetic mouse models for skin research: strategies and resources.MYC: Master Regulator of Immune Privilege.Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex.Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice.Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.Inducible and selective transgene expression in murine vascular endothelium.Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine.
P2860
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P2860
Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Conditional expression of the ...... expression in transgenic mice.
@en
Conditional expression of the ...... expression in transgenic mice.
@nl
type
label
Conditional expression of the ...... expression in transgenic mice.
@en
Conditional expression of the ...... expression in transgenic mice.
@nl
prefLabel
Conditional expression of the ...... expression in transgenic mice.
@en
Conditional expression of the ...... expression in transgenic mice.
@nl
P2093
P2860
P356
P1433
P1476
Conditional expression of the ...... expression in transgenic mice.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202673
P407
P577
1999-06-01T00:00:00Z
P5875
P6179
1000245289