Chronic airway infection/inflammation induces a Ca2+i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia.
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Mechanisms of the noxious inflammatory cycle in cystic fibrosisVAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cellsThe lactoperoxidase system links anion transport to host defense in cystic fibrosisEpithelial Anion Transport as Modulator of Chemokine SignalingAirway epithelial homeostasis and planar cell polarity signaling depend on multiciliated cell differentiationBronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.Azithromycin treatment alters gene expression in inflammatory, lipid metabolism, and cell cycle pathways in well-differentiated human airway epithelia.Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis miceThe ER stress transducer IRE1β is required for airway epithelial mucin productionCystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure.The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cellsAbnormal n-6 fatty acid metabolism in cystic fibrosis is caused by activation of AMP-activated protein kinaseAAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.Cystic fibrosis remodels the regulation of purinergic signaling by NTPDase1 (CD39) and NTPDase3Mechanisms of action and clinical application of macrolides as immunomodulatory medications.Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes.Localization of Burkholderia cepacia complex bacteria in cystic fibrosis lungs and interactions with Pseudomonas aeruginosa in hypoxic mucus.Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells.Cystic fibrosis bronchial epithelial cells are lipointoxicated by membrane palmitate accumulation.Potential of anti-inflammatory treatment for cystic fibrosis lung disease.Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores.Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial CellsE-NTPDases in human airways: Regulation and relevance for chronic lung diseasesProinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia.Effective mucus clearance is essential for respiratory health.Update in cystic fibrosis 2005X-Box-Binding Protein 1 and Innate Immune Responses of Human Cystic Fibrosis Alveolar Macrophages.Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect.Regulation of interleukin-6 secretion by the two-pore-domain potassium channel Trek-1 in alveolar epithelial cells.Cystic fibrosis: a mucosal immunodeficiency syndrome.Inflammation promotes airway epithelial ATP release via calcium-dependent vesicular pathways.Role of IRE1α/XBP-1 in Cystic Fibrosis Airway Inflammation.Role of endoplasmic reticulum stress in cystic fibrosis-related airway inflammatory responsesBronchial brushings for investigating airway inflammation and remodelling.The UPR and lung disease.The integrated stress response in lung disease.Role of Ca2+ in responses of airway epithelia to Pseudomonas aeruginosa, flagellin, ATP, and thapsigargin.Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epitheliumCalcium-modulated chloride pathways contribute to chloride flux in murine cystic fibrosis-affected macrophages.
P2860
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P2860
Chronic airway infection/inflammation induces a Ca2+i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@en
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@nl
type
label
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@en
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@nl
prefLabel
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@en
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@nl
P2093
P356
P1476
Chronic airway infection/infla ...... tic fibrosis airway epithelia.
@en
P2093
Anthony M Paradiso
Carla M Pedrosa Ribeiro
Juan Perez-Vilar
Lisa Jones
Richard C Boucher
Ute Schwab
Wanda O'neal
P304
17798-17806
P356
10.1074/JBC.M410618200
P407
P577
2005-03-03T00:00:00Z