Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate.
about
Metabolic Inflammation-Differential Modulation by Dietary ConstituentsType 2 Diabetes in Non-Alcoholic Fatty Liver Disease and Hepatitis C Virus Infection--Liver: The "Musketeer" in the SpotlightLinking obesity with type 2 diabetes: the role of T-betImplications of mitochondrial uncoupling in skeletal muscle in the development and treatment of obesityDefect of insulin signal in peripheral tissues: Important role of ceramideCeramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocationPalmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondriaMetformin and exercise reduce muscle FAT/CD36 and lipid accumulation and blunt the progression of high-fat diet-induced hyperglycemiaMusclin, a novel skeletal muscle-derived secretory factorInsulin resistance and elevated triglyceride in muscle: more important for survival than "thrifty" genes?Mechanisms for insulin resistance: common threads and missing linksRole of ceramide in diabetes mellitus: evidence and mechanisms.Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivityProtein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).Effect of short-term starvation versus high-fat diet on intramyocellular triglyceride accumulation and insulin resistance in physically fit men.Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated HepatocytesAdipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsivenessElevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjectsInsulin increases ceramide synthesis in skeletal muscleMammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Sphingolipids in obesity, type 2 diabetes, and metabolic disease.Influence of fish oil on skeletal muscle mitochondrial energetics and lipid metabolites during high-fat diet.Effects of endurance exercise and high-fat diet on insulin resistance and ceramide contents of skeletal muscle in sprague-dawley ratsSaturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors.Alteration of microRNA expression correlates to fatty acid-mediated insulin resistance in mouse myoblasts.Fatty acids increase glucose uptake and metabolism in C2C12 myoblasts stably transfected with human lipoprotein lipase.Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 myotubes.Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity.Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.Mitochondrial dysfunction and insulin resistance: an update.Cancer treatment strategies targeting sphingolipid metabolism.Acylcarnitines: potential implications for skeletal muscle insulin resistance.The evolution of insulin resistance in muscle of the glucose infused ratDifferential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistanceLysophosphatidylcholine as an effector of fatty acid-induced insulin resistance.PPAR-gamma expression modulates insulin sensitivity in C2C12 skeletal muscle cellsMetabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system.Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubesMuscle ectopic fat deposition contributes to anabolic resistance in obese sarcopenic old rats through eIF2α activation.
P2860
Q26748868-2870AA91-62A4-4358-99E2-87E7E596EE03Q26752583-8AF1D484-BED5-467B-89B8-C137F109F7BBQ26830915-93095971-D285-4F6F-B989-1C7F8B3988FCQ26852995-0811DD7A-2A91-4135-9CF1-4B75D0518FB2Q27690875-933706D3-04FE-42CE-A452-CBAFF469AE56Q28348363-BC970F09-61A9-4C09-A707-989FB6CCB310Q28573343-4542B0A9-B129-4F88-AC4D-12E66C2DA4D7Q28581219-4E694283-9892-4CB3-9F26-38298F75BFE6Q28585414-6BFB1F16-9491-45D4-82AB-41F33BDDC14BQ28766365-BC6A82A1-2868-497E-805F-389567E1A784Q29620447-7C8679B1-D4F5-4AE2-A138-C077F497A804Q30351934-05384A85-9F24-470A-93A3-F34AF103F641Q30423827-E4AA0612-B1CC-4FC8-8BE9-3FFB04D3F475Q33184955-9BCE6C65-879D-4250-8D5E-5418159F5EDDQ33240514-3F9560E8-3764-4CEA-AB87-D84584FF1AA3Q33631394-06C5D59A-D54F-4E4F-9754-19B44FDCD80EQ33642894-F9DCCC4A-F722-4F9E-9A62-15C98F5C97E0Q33723943-99CC4327-7172-4ECB-8433-CA81EA2D0B54Q33736297-6687A627-C04F-4528-AD23-810990ADB9C8Q33829692-B1286131-5B52-4079-8A26-7CDE8C66077CQ33880588-DD7914B4-C51E-4372-A8AF-108DF525B402Q33976122-286759D6-D370-4E9B-92F6-2BE213074DE0Q34101886-38B3A7A1-3B2F-432F-9BFC-5007A7B8A030Q34132356-DBA2A294-ADAB-436C-8534-9D7141D883E6Q34156501-D295D0F1-2133-4058-9D70-231EE3B58C74Q34215206-F0051A52-579E-4C71-8716-FCB2A145BF42Q34251073-95DA224F-2AD1-4EAC-AC86-31EEB23C9A55Q34333517-5332CB9B-FE12-4C31-BC24-879AF25F0022Q34364833-C7F7E65C-D729-4A48-9278-EBEF00E286B4Q34476883-F7FC9E77-F958-49E6-9FA6-080F9EDC3EDFQ34668089-F4F72348-29BD-4E48-9B13-52C87FFD9AB4Q34790629-9DF47511-BB6D-46DC-B50B-D2FE5213FC7CQ34847808-2983CC23-4DD5-4DD5-911D-2E641EC63780Q34921325-BF5C6272-4ED3-4E26-9E0C-EA854DC52F54Q34947370-7CFB3FA9-6715-4682-AD0E-73AACEC92F7BQ34955984-F8ACA28E-3BD7-4E93-8D0F-B74B9F11DC62Q35048456-6381867A-1372-43F7-BA43-ED37D2F128D8Q35063267-941CFA4F-A9A5-4C47-A848-888BCC6A6813Q35078615-8A5241EF-7947-467C-9A5F-B70DB3EDDC7DQ35080584-45CFF7D5-D63C-40B4-B969-13DAC4313CD1
P2860
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Ceramide generation is suffici ...... lls pretreated with palmitate.
@en
Ceramide generation is suffici ...... lls pretreated with palmitate.
@nl
type
label
Ceramide generation is suffici ...... lls pretreated with palmitate.
@en
Ceramide generation is suffici ...... lls pretreated with palmitate.
@nl
prefLabel
Ceramide generation is suffici ...... lls pretreated with palmitate.
@en
Ceramide generation is suffici ...... lls pretreated with palmitate.
@nl
P2093
P356
P1476
Ceramide generation is suffici ...... lls pretreated with palmitate.
@en
P2093
Schmitz-Peiffer C
P304
24202-24210
P356
10.1074/JBC.274.34.24202
P407
P577
1999-08-01T00:00:00Z