Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1). - Wikidata - wikimedia - TriplyDB

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

http://www.wikidata.org/entity/Q33184955

about

Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice Mechanisms of action of glucagon-like peptide 1 in the pancreas The Potential Protective Action of Vitamin D in Hepatic Insulin Resistance and Pancreatic Islet Dysfunction in Type 2 Diabetes Mellitus Potential roles of GPR120 and its agonists in the management of diabetes The role of the p53 tumor suppressor in metabolism and diabetes Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of β-cells via JNK, p38 MAPK and p53 pathways.PKCdelta blues for the beta-cell β-cell mass in people with type 2 diabetes.Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.Glucolipotoxicity of the pancreatic beta cell.Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms.Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.Adiponectin-induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion.Inhibitory effect of LXR activation on cell proliferation and cell cycle progression through lipogenic activity.Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans.Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.Protein tyrosine phosphatase-1B modulates pancreatic β-cell mass Morin attenuates tau hyperphosphorylation by inhibiting GSK3β.Glucolipotoxicity impairs ceramide flow from the endoplasmic reticulum to the Golgi apparatus in INS-1 β-cells FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells.Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867 Imaging ectopic fat deposition in Caenorhabditis elegans muscles using nonlinear microscopy.Plastidial fatty acid levels regulate resistance gene-dependent defense signaling in Arabidopsis Protective role of oleic acid against cardiovascular insulin resistance and in the early and late cellular atherosclerotic process.Beta-cell mass plasticity in type 2 diabetes.A simple matter of life and death-the trials of postnatal Beta-cell mass regulation AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic β-cell Apoptosis via Differential Downstream Mechanisms.Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans.On the role of IRS2 in the regulation of functional beta-cell mass.Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.Phosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes.Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition Update on the protective molecular pathways improving pancreatic beta-cell dysfunction Glucolipotoxicity: fuel excess and beta-cell dysfunction.Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction.

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P2860

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

http://www.wikidata.org/entity/Q33184955

description

2002 nî lūn-bûn

@nan

2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

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Protein kinase B/Akt prevents ...... pancreatic beta-cells (INS-1).

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Protein kinase B/Akt prevents ...... pancreatic beta-cells (INS-1).

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P1433

Journal of Biological Chemistry

P1476

Protein kinase B/Akt prevents ...... pancreatic beta-cells (INS-1).

@en

P2093

Christian E Wrede

http://www.w3.org/2001/XMLSchema#string

Christopher J Rhodes

http://www.w3.org/2001/XMLSchema#string

Isabelle Briaud

http://www.w3.org/2001/XMLSchema#string

Lorna M Dickson

http://www.w3.org/2001/XMLSchema#string

Melissa K Lingohr

http://www.w3.org/2001/XMLSchema#string

P2860

Ceramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocation

Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

Cell cycle and death control: long live Forkheads

Caspases: enemies within

Cellular survival: a play in three Akts

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

Cellular mechanisms of insulin resistance

The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction.

P304

49676-49684

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scholarly article

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10.1074/JBC.M208756200

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P433

51

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P478

277

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2002-10-21T00:00:00Z

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12393870

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P921