Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
about
Synaptic vesicle pools and dynamicsPrimary afferent activation of thermosensitive TRPV1 triggers asynchronous glutamate release at central neuronsBorna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling.A dual-Ca2+-sensor model for neurotransmitter release in a central synapseDistinct initial SNARE configurations underlying the diversity of exocytosisAstrocytes optimize the synaptic transmission of informationA limited contribution of Ca2+ current facilitation to paired-pulse facilitation of transmitter release at the rat calyx of HeldPresynaptic Calmodulin targets: lessons from structural proteomics.Munc18-1 is a dynamically regulated PKC target during short-term enhancement of transmitter releaseAcute dynamin inhibition dissects synaptic vesicle recycling pathways that drive spontaneous and evoked neurotransmission.Quantitative analysis of synaptic release at the photoreceptor synapseUbiquitination acutely regulates presynaptic neurotransmitter release in mammalian neuronsDOC2B and Munc13-1 differentially regulate neuronal network activity.Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release.Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels.The SNARE complex in neuronal and sensory cells.Dynamin-1 deletion enhances post-tetanic potentiation and quantal size after tetanic stimulation at the calyx of Held.Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca(2+) channel-vesicle coupling.Fast retrieval and autonomous regulation of single spontaneously recycling synaptic vesicles.Nanodomain coupling explains Ca²⁺ independence of transmitter release time course at a fast central synapse.Differential regulation of spontaneous and evoked neurotransmitter release at central synapses.Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor.A sequential vesicle pool model with a single release sensor and a Ca(2+)-dependent priming catalyst effectively explains Ca(2+)-dependent properties of neurosecretion.Axonal noise as a source of synaptic variability.Calcium cooperativity of exocytosis as a measure of Ca²+ channel domain overlap.An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS SynapseShaping Neuronal Network Activity by Presynaptic MechanismsReduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapsesCalmodulin as a major calcium buffer shaping vesicular release and short-term synaptic plasticity: facilitation through buffer dislocationPosttetanic potentiation critically depends on an enhanced Ca(2+) sensitivity of vesicle fusion mediated by presynaptic PKC.Molecular underpinnings of synaptic vesicle pool heterogeneity.Structural transitions in the synaptic SNARE complex during Ca2+-triggered exocytosis.Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABADynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasisAbnormal neurotransmitter release underlying behavioral and cognitive disorders: toward concepts of dynamic and function-specific dysregulation.Nanodomain coupling between Ca²⁺ channels and sensors of exocytosis at fast mammalian synapses.Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca2+ channels via microdomain coupling.Brief wide-field photostimuli evoke and modulate oscillatory reverberating activity in cortical networksMechanisms of tonic, graded release: lessons from the vertebrate photoreceptor.Selective saturation of slow endocytosis at a giant glutamatergic central synapse lacking dynamin 1
P2860
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P2860
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
@en
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
@nl
type
label
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
@en
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
@nl
prefLabel
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
@en
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.
@nl
P2860
P356
P1433
P1476
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion
@en
P2093
Ralf Schneggenburger
Xuelin Lou
P2860
P2888
P304
P356
10.1038/NATURE03568
P407
P577
2005-05-01T00:00:00Z
P6179
1043012383