The P2Y14 receptor of airway epithelial cells: coupling to intracellular Ca2+ and IL-8 secretion.
about
An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiationHuman P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups.UDP-glucose acting at P2Y14 receptors is a mediator of mast cell degranulationMechanisms of action and clinical application of macrolides as immunomodulatory medications.Signalling and pharmacological properties of the P2Y receptor.UDP is a competitive antagonist at the human P2Y14 receptorEnhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.Coupling of P2Y receptors to G proteins and other signaling pathwaysRenal intercalated cells sense and mediate inflammation via the P2Y14 receptor.P2Y6 receptor-mediated proinflammatory signaling in human bronchial epithelia.UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptorThe UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.Extracellular ATP and other nucleotides-ubiquitous triggers of intercellular messenger release.Regulation of surfactant secretion in alveolar type II cells.Chemotactic activity of extracellular nucleotideson human immune cells.Structural and functional evolution of the P2Y(12)-like receptor group.Endoplasmic reticulum/golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling moleculesPredicting Diagnostic Gene Biomarkers for Non-Small-Cell Lung Cancer.Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucoseUDP-glucose promotes neutrophil recruitment in the lung.Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor.Selective induction of P2Y14 receptor by RANKL promotes osteoclast formation.Quantification of extracellular UDP-galactose.Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epitheliumCa2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides.Coordinated release of nucleotides and mucin from human airway epithelial Calu-3 cells.Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms.Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury.Transcriptomic Analysis of Lung Tissue from Cigarette Smoke-Induced Emphysema Murine Models and Human Chronic Obstructive Pulmonary Disease Show Shared and Distinct Pathways.Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling.Nucleotides induce IL-6 release from human airway epithelia via P2Y2 and p38 MAPK-dependent pathways.
P2860
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P2860
The P2Y14 receptor of airway epithelial cells: coupling to intracellular Ca2+ and IL-8 secretion.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@en
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@nl
type
label
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@en
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@nl
prefLabel
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@en
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@nl
P2093
P2860
P356
P1476
The P2Y14 receptor of airway e ...... lular Ca2+ and IL-8 secretion.
@en
P2093
Daniel Myrtek
Francesco Di Virgilio
Hans Bayer
J Christian Virchow
Johannes Norgauer
Manfred W Ziegenhagen
Marco Idzko
Stephan Sorichter
Tobias Müller
Werner Luttmann
P2860
P304
P356
10.1165/RCMB.2005-0181OC
P577
2005-08-18T00:00:00Z