Protein kinase C activation stimulates the phosphorylation and internalization of the sst2A somatostatin receptor.
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Fine-tuning somatostatin receptor signalling by agonist-selective phosphorylation and dephosphorylation: IUPHAR Review 5Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalizationAgonist-induced phosphorylation of somatostatin receptor subtype 1 (sst1). Relationship to desensitization and internalization.Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation.Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation.Ligand-dependent mechanisms of sst2A receptor trafficking: role of site-specific phosphorylation and receptor activation in the actions of biased somatostatin agonists.Somatostatin receptor biology in neuroendocrine and pituitary tumours: part 1--molecular pathways.Dual mode of glucagon receptor internalization: role of PKCα, GRKs and β-arrestins.A functional comparison of recombinant and native somatostatin sst2 receptor variants in epithelia.Inhibitory effect of octreotide on gastric cancer growth via MAPK pathway.Involvement of somatostatin receptor subtypes in membrane ion channel modification by somatostatin in pituitary somatotropes.Illuminating somatostatin analog action at neuroendocrine tumor receptorsPKC controls HGF-dependent c-Met traffic, signalling and cell migration.Internalization-defective mutants of somatostatin receptor subtype 2 exert normal signaling functions in hematopoietic cells.Somatostatin receptor type 5 modulates somatostatin receptor type 2 regulation of adrenocorticotropin secretion.Identification of human somatostatin receptor 2 domains involved in internalization and signaling in QGP-1 pancreatic neuroendocrine tumor cell line.Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors.Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation.Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization.Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: evidence for regulation of nerve growth factor-induced differentiation.Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation.Second messenger-dependent protein kinases and protein synthesis regulate endogenous secretin receptor responsiveness.Casein kinase II sites in the intracellular C-terminal domain of the thyrotropin-releasing hormone receptor and chimeric gonadotropin-releasing hormone receptors contribute to beta-arrestin-dependent internalization.Role of the human V1 vasopressin receptor COOH terminus in internalization and mitogenic signal transduction.Receptor-mediated endocytosis of Neisseria gonorrhoeae into primary human urethral epithelial cells: the role of the asialoglycoprotein receptor.Agonist-independent desensitization and internalization of the human platelet-activating factor receptor by coumermycin-gyrase B-induced dimerization.International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature
P2860
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P2860
Protein kinase C activation stimulates the phosphorylation and internalization of the sst2A somatostatin receptor.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@en
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@nl
type
label
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@en
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@nl
prefLabel
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@en
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@nl
P2093
P2860
P356
P1476
Protein kinase C activation st ...... e sst2A somatostatin receptor.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.8.5591
P407
P577
2000-02-01T00:00:00Z