Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.
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Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretionDifferential activation of innate immune responses by adenovirus and adeno-associated virus vectorsCloning and expression of rat pancreatic beta-cell malonyl-CoA decarboxylaseCNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretionInhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinaseStable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide productionTrefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function.Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technologyContamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.Raptor regulates functional maturation of murine beta cells.Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathwaysLong-term survival of allograft murine islets coated via covalently stabilized polymers.Interactions between insulin resistance and insulin secretion in the development of glucose intolerance.Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1Gene therapy in diabetes.Anthocyanins-rich extract of wild Chinese blueberry protects glucolipotoxicity-induced INS832/13 β-cell against dysfunction and death.Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell functionMuscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibilityDNA methylation directs functional maturation of pancreatic β cells.Epigenetic programming of glucose-regulated insulin release.Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7-37).Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic controlDominant form of congenital hyperinsulinism maps to HK1 region on 10q.Obesity and lipid stress inhibit carnitine acetyltransferase activityAdenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.FFAR3 modulates insulin secretion and global gene expression in mouse islets.Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10.The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions.Congenital hyperinsulinism caused by hexokinase I expression or glucokinase-activating mutation in a subset of β-cells.PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moietiesExposure to glibenclamide increases rat beta cells sensitivity to glucose.Assessing replication and beta cell function in adenovirally-transduced isolated rodent islets.Nutrient sensing in pancreatic islets: lessons from congenital hyperinsulinism and monogenic diabetes.
P2860
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P2860
Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@en
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@nl
type
label
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@en
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@nl
prefLabel
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@en
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@nl
P2093
P921
P1476
Overexpression of hexokinase I ...... ot stimulatory glucose levels.
@en
P2093
BeltrandelRio H
Johnson JH
Newgard CB
P304
21234-21238
P407
P577
1994-08-01T00:00:00Z