Rho kinase as a novel molecular therapeutic target for hypertensive internal anal sphincter.
about
Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCKRole of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone.Aging-associated oxidative stress leads to decrease in IAS tone via RhoA/ROCK downregulationImmunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cellsRole of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle.Heme oxygenase-1 upregulation modulates tone and fibroelastic properties of internal anal sphincterSmooth muscle-protein translocation and tissue functionRole of rho kinase in the functional and dysfunctional tonic smooth muscles.Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cellsRole of SM22 in the differential regulation of phasic vs. tonic smooth muscle.RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincterBimodal effect of oxidative stress in internal anal sphincter smooth muscle.Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function.SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrumROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progressionRole of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting.COX-1 vs. COX-2 as a determinant of basal tone in the internal anal sphincter.3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylationRhoA/Rho-kinase: pathophysiologic and therapeutic implications in gastrointestinal smooth muscle tone and relaxation.Gastrointestinal tone; its genesis and contribution to the physical processes of digestion.Basal internal anal sphincter tone, inhibitory neurotransmission, and other factors contributing to the maintenance of high pressures in the anal canal.Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133aEffects of Rho-kinase inhibition on myosin light chain phosphorylation and obstruction-induced detrusor overactivity.Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle.Internal anal sphincter nerves - a macroanatomical and microscopic description of the extrinsic autonomic nerve supply of the internal anal sphincter.In vivo magnetofection: a novel approach for targeted topical delivery of nucleic acids for rectoanal motility disorders.Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone.
P2860
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P2860
Rho kinase as a novel molecular therapeutic target for hypertensive internal anal sphincter.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Rho kinase as a novel molecula ...... nsive internal anal sphincter.
@en
Rho kinase as a novel molecula ...... nsive internal anal sphincter.
@nl
type
label
Rho kinase as a novel molecula ...... nsive internal anal sphincter.
@en
Rho kinase as a novel molecula ...... nsive internal anal sphincter.
@nl
prefLabel
Rho kinase as a novel molecula ...... nsive internal anal sphincter.
@en
Rho kinase as a novel molecula ...... nsive internal anal sphincter.
@nl
P1433
P1476
Rho kinase as a novel molecula ...... ensive internal anal sphincter
@en
P2093
Chirag A Patel
Marcio A F De Godoy
P304
P356
10.1053/J.GASTRO.2006.03.043
P407
P577
2006-07-01T00:00:00Z