Protein kinase-A phosphorylates titin in human heart muscle and reduces myofibrillar passive tension.
about
The role of titin and extracellular matrix remodelling in heart failure with preserved ejection fractionOngoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray?Titin-based tension in the cardiac sarcomere: molecular origin and physiological adaptationsThe molecular mechanisms of offspring effects from obese pregnancyHeart failure with preserved ejection fractionWhat global diastolic function is, what it is not, and how to measure itTargeting the sarcomere to correct muscle functionTropomyosin de-phosphorylation in the heart: what are the consequences?Small and large animal models in cardiac contraction research: advantages and disadvantagesSingle acute stress-induced progesterone and ovariectomy alter cardiomyocyte contractile function in female rats.Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffnessPhysiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscleNew strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes.Probing muscle ankyrin-repeat protein (MARP) structure and functionAcute exercise modifies titin phosphorylation and increases cardiac myofilament stiffnessThe giant protein titin: a regulatory node that integrates myocyte signaling pathways.Muscle giants: molecular scaffolds in sarcomerogenesis.Diastolic myofilament dysfunction in the failing human heart.Beneficial effects of SR33805 in failing myocardium.Emerging importance of oxidative stress in regulating striated muscle elasticity.Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles.Development of dilated cardiomyopathy in Bmal1-deficient miceA novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics.The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.Modulation of titin-based stiffness by disulfide bonding in the cardiac titin N2-B unique sequenceSynchronous in situ ATPase activity, mechanics, and Ca2+ sensitivity of human and porcine myocardium.Cardiac titin: a multifunctional giantConformation-regulated mechanosensory control via titin domains in cardiac muscle.Molecular and cellular basis for diastolic dysfunction.Tuning the molecular giant titin through phosphorylation: role in health and disease.Mechanical properties of respiratory musclesAdrenergic signaling in heart failure: a balance of toxic and protective effects.Cell- and molecular-level mechanisms contributing to diastolic dysfunction in HFpEFProtein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials.Myocardial reverse remodeling: how far can we rewind?Myofilaments: Movers and Rulers of the Sarcomere.Raf kinase inhibitor protein: lessons of a better way for β-adrenergic receptor activation in the heart.The role of protein kinase C-mediated phosphorylation of sarcomeric proteins in the heart-detrimental or beneficial?Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes.
P2860
Q26765101-6C5BCFFB-2ABE-4DCD-8195-4BA8E01BF940Q26800197-E767DBAC-B01F-4B47-9D67-1603AF08B7BDQ26996063-A54CA9E0-9427-4563-8B76-6FB35A99AA80Q27008079-DD582C07-171B-48BD-A4D3-781AE48C8F3BQ27024008-393F1FDD-330A-468F-B669-EA4C9FEF1A93Q28087043-200D0FA9-2817-4D1B-AF05-9495903D5FC0Q28260629-FA5EAD8B-1603-4CF0-8C96-6169EE1C5AB3Q28293301-3EEFECDB-DC65-4CDE-9FE9-A4C52426F476Q28658055-CD300C00-D01C-49BC-B104-683A2C291479Q33725423-35C48BCA-9480-4797-B598-C0D6CE18ECCCQ33787977-0546AC4D-936F-4C37-8B00-21A53043B59CQ33961078-F63E78BF-833C-4946-A362-A6D04A7FEB7AQ34375466-1696B0B3-5496-483C-8AE4-D519C4A888AAQ34433678-5A9EEB5D-A141-4B3D-9DD9-6AF03A727517Q34547240-02BB08ED-AB2E-4FBE-817B-CA6E07936BDEQ34696141-EE7D4BA2-8784-451C-9FF3-69D593898ADFQ34793699-C4FE7815-C779-4C05-B559-1C92A081E23AQ35042592-6E58685A-428F-429A-9823-AEEAEA2665DAQ35114766-BF430C9D-1931-4806-92DE-DFA43EA04503Q35155257-B1A82F52-AAEC-4D99-AC5D-17EB478EB4D9Q35964925-B2EBF558-F599-49DD-B478-4ED8FFBA4FD0Q36176071-07A4CC34-13E7-40F2-A301-6F33E7335347Q36215905-8EB616A7-BE44-407D-92BB-F8C6141B45ECQ36504127-7A61132C-01BD-4040-A3C8-D1CED2FBA7DFQ36507217-C22F3E93-6479-4FB0-9ABA-69ADEF2CE85AQ37281915-C2E7DECA-D33B-4E20-963D-817EFC9F81E1Q37405997-7C6216B5-63A4-439A-8AFD-9413F8BD6FDAQ37755897-D50BC5AF-7195-47C1-A6D5-8DF7A8A8C910Q37846578-645820FC-4D55-4844-9332-332C8C96237FQ38038531-1A47E3C3-3CBD-4281-B5CA-43553C65F6C8Q38072172-4F2F0739-1F58-4C72-AAC4-BFE4FE103848Q38165141-F7FE7602-719F-469A-B97B-9967378BE82DQ38195518-F9D288E8-CBBB-4FEE-AB49-ED3355301C06Q38441801-49C3730F-2E8B-4AD4-93D3-C43002289BFFQ38670275-75ADD28F-81BF-4025-AEEC-4DB4CE57704DQ38780883-29F5EFF4-1083-4849-83BC-0AC0CB6C8ABFQ39195665-3702ECE2-1768-48A4-89B6-E4973270646BQ39263982-0BA19291-B509-4C67-B232-D4A5C157EE1CQ39310482-D76358F3-BD50-4BA9-BAE4-63D5E2844010Q39310690-C09D5925-9D43-45F4-B2CD-6C446F6A6C35
P2860
Protein kinase-A phosphorylates titin in human heart muscle and reduces myofibrillar passive tension.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@en
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@nl
type
label
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@en
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@nl
prefLabel
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@en
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@nl
P1476
Protein kinase-A phosphorylate ...... myofibrillar passive tension.
@en
P2093
Martina Krüger
Wolfgang A Linke
P2860
P2888
P304
P356
10.1007/S10974-006-9090-5
P577
2006-08-04T00:00:00Z
P5875
P6179
1008163814