Signal processing at the Ras circuit: what shapes Ras activation patterns?
about
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathwayOpen cascades as simple solutions to providing ultrasensitivity and adaptation in cellular signalingSwitches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination systemDBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation resultsCoupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movementAn empirical Bayesian approach for model-based inference of cellular signaling networksSignaling through receptors and scaffolds: independent interactions reduce combinatorial complexityCell-signalling dynamics in time and space.Compartment-specific feedback loop and regulated trafficking can result in sustained activation of Ras at the Golgi.Absolute Quantification of Endogenous Ras Isoform AbundanceA Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST.Current challenges in quantitative modeling of epidermal growth factor signaling.Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.Feedback activation of neurofibromin terminates growth factor-induced Ras activation.Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.Models at the single cell level.Four-dimensional dynamics of MAPK information processing systems.Mathematical Justification of Expression-Based Pathway Activation Scoring (PAS).Systems biology of cellular membranes: a convergence with biophysics.Mechanistic modeling to investigate signaling by oncogenic Ras mutants.Kinetic mechanisms for overexpression insensitivity and oncogene cooperation.Simplification of stochastic chemical reaction models with fast and slow dynamics.Goldbeter-Koshland model for open signaling cascades: a mathematical study.The impact of the regulatory design on the response of epidermal growth factor receptor-mediated signal transduction towards oncogenic mutations.New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling.Quantitative Systems Pharmacology Analysis of KRAS G12C Covalent Inhibitors.
P2860
Q24534940-2A15562E-4569-411B-B09E-923DF58ACEDEQ24621885-26BF46F0-198F-461D-8B57-4B7C3F44F4D6Q28478440-E710E782-FE19-4FFA-9828-D30BE80E3C9EQ30496215-EC163E16-2BC5-4C4E-BEFC-5C5751D8B555Q30844726-DA4164C3-3342-433E-97F5-3760952CEA14Q30878109-1A75AF49-7475-444A-8ADF-9D40FD57D3A8Q34350920-11846C64-2ED0-4A80-B4E9-D772F5E236F6Q34495098-D6F3B48E-AF51-44DF-85AB-5A081A8736CAQ34581000-D1AB31C2-A7F7-43C6-A630-1724A4C81E81Q35839061-98D3B067-4B18-4CAB-B5E7-5F55017D972DQ36032370-C5CD10B0-90BE-4FB1-B95C-F3A8017D7C59Q36313362-6C4EE03A-5957-4E03-A822-B6BE9B40100BQ36559220-F050E9F4-BB7B-4DDC-9B65-F4A79B67CFE8Q36560923-4E6C4F3C-052A-4687-9F6B-A494AC74A55BQ37196175-41019F1D-B7A6-43A6-A06B-E01E2D9B2F37Q37492381-6B8E4EA2-DDB2-48FC-B8C0-FD3781F9B514Q37698293-A4D3F0B6-A791-4FE2-BA45-ECE1357C2811Q38604285-FFDA1D98-8B66-4004-ACBB-ACFE1A9AFC8BQ39285785-878ED753-6559-4F57-8113-0F685CDD16FBQ39727752-57BD70C7-9F69-48D4-8043-27948DBD6B84Q42446027-4C75166A-BE41-4267-A8BA-7E0462D4FE31Q43176715-AA6161C6-0533-4255-94EB-755AE71EDE90Q51759545-B35B03DB-DDD9-4049-9055-B7B1F6A53276Q51904547-94004232-4DC0-4B39-AF35-12CFDFBF3C25Q52666594-947E4FF0-16C3-4E05-9029-0FF816F50E65Q55384002-27548BB9-9839-420B-A503-EC23E1602E5B
P2860
Signal processing at the Ras circuit: what shapes Ras activation patterns?
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@en
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@nl
type
label
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@en
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@nl
prefLabel
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@en
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@nl
P2093
P50
P356
P1433
P1476
Signal processing at the Ras circuit: what shapes Ras activation patterns?
@en
P2093
N I Markevich
P304
P356
10.1049/SB:20045003
P577
2004-06-01T00:00:00Z