Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.
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Metabolic Inflammation-Differential Modulation by Dietary ConstituentsTransamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretionPPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunctionGlucolipotoxicity of the pancreatic beta cell.Quantification of lipid droplets and associated proteins in cellular models of obesity via high-content/high-throughput microscopy and automated image analysis.Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass.Geniposide regulates glucose-stimulated insulin secretion possibly through controlling glucose metabolism in INS-1 cells.Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes.Mitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role?Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity.Glucolipotoxicity: fuel excess and beta-cell dysfunction.Glucolipotoxicity of the pancreatic beta-cell: myth or reality?Mitochondrial dynamics and morphology in beta-cells.The Pancreatic β-Cell: A Bioenergetic Perspective.Adropin deficiency worsens HFD-induced metabolic defectsTranscribing β-cell mitochondria in health and disease.Maternal high-fat diet is associated with altered pancreatic remodelling in mice offspring.Adaptation to intermittent stress promotes maintenance of beta-cell compensation: comparison with food restriction.
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P2860
Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.
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2006 nî lūn-bûn
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Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
@en
Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
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type
label
Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
@en
Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
@nl
prefLabel
Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
@en
Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
@nl
P2093
P50
P1433
P1476
Enhanced mitochondrial metabol ...... L/6J mice fed a high-fat diet.
@en
P2093
M Dekker Nitert
P2888
P356
10.1007/S00125-006-0464-4
P577
2006-11-09T00:00:00Z