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140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometryIncreased Melatonin Signaling Is a Risk Factor for Type 2 DiabetesProteomic studies in animal models of diabetes.Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetesMitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells.HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13.TCF7L2 is a master regulator of insulin production and processing.Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretionPhotocoagulation of human retinal pigment epithelium in vitro: unravelling the effects on ARPE-19 by transcriptomics and proteomics.Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person SyndromeSerotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans.Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets.Lipases in the pancreatic beta-cell: implications for insulin secretion.Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls.Differential effects of three echovirus strains on cell lysis and insulin secretion in beta cell derived lines.Influence of a HTR2B Stop Codon on Glucagon Homeostasis and Glucose Excursion in Non-Diabetic Men.Apelin is a novel islet peptide.Early human pregnancy serum cytokine levels predict autoimmunity in offspring.Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass.Serotonin (5-HT) and 5-HT2A receptor agonists suppress lipolysis in primary rat adipose cells.MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.Microphthalmia transcription factor regulates pancreatic β-cell function.Serum cytokine pattern in young children with screening detected coeliac disease.A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis.The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis.Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact.Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats.Amylin alters human brain pericyte viability and NG2 expression.Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 (GLP-1) is Governed by an Activated Glutamate Dehydrogenase.The pathogenetic role of β-cell mitochondria in type 2 diabetes.Brain alpha-amylase - a novel energy regulator important in Alzheimer disease?Characterization of resident lymphocytes in human pancreatic islets.The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events.An Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes May Be Related to HLA-DQ8.Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance.The effects of a HTR2B stop codon and testosterone on energy metabolism and beta cell function among antisocial Finnish males.CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.Altered serotonin (5-HT) 1D and 2A receptor expression may contribute to defective insulin and glucagon secretion in human type 2 diabetes.
P50
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P50
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6507604365
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P496
0000-0003-0675-7576