Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
about
Discovery of FabH/FabF inhibitors from natural products.Role of fatty acid de novo biosynthesis in polyhydroxyalkanoic acid (PHA) and rhamnolipid synthesis by pseudomonads: establishment of the transacylase (PhaG)-mediated pathway for PHA biosynthesis in Escherichia coliDiscovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic propertiesExposure of sink drain microcosms to triclosan: population dynamics and antimicrobial susceptibilityThe 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniaeMolecular basis of triclosan activityInhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanismStructural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductaseStructure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthaseCrystal structure of enoyl-acyl carrier protein reductase (FabK) fromStreptococcus pneumoniaereveals the binding mode of an inhibitorDesign and Synthesis of Aryl Ether Inhibitors of theBacillus AnthracisEnoyl-ACP ReductaseTriclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosisMode of Action, In Vitro Activity, and In Vivo Efficacy of AFN-1252, a Selective Antistaphylococcal FabI InhibitorStructure of the Yersinia pestis FabV Enoyl-ACP Reductase and Its Interaction with Two 2-Pyridone InhibitorsPyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhAResistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) AntibioticsMechanism of triclosan inhibition of bacterial fatty acid synthesisConsumer antibacterial soaps: effective or just risky?Use of germicides in the home and the healthcare setting: is there a relationship between germicide use and antibiotic resistance?Dual-resolution molecular dynamics simulation of antimicrobials in biomembranesInhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachloropheneTriclosan: A Widespread Environmental Toxicant with Many Biological EffectsA new mechanism for anaerobic unsaturated fatty acid formation in Streptococcus pneumoniaeMechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureusHeterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZFunction of heterologous Mycobacterium tuberculosis InhA, a type 2 fatty acid synthase enzyme involved in extending C20 fatty acids to C60-to-C90 mycolic acids, during de novo lipoic acid synthesis in Saccharomyces cerevisiaeThe enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilisMechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia malleiCharacterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesisThe MexJK efflux pump of Pseudomonas aeruginosa requires OprM for antibiotic efflux but not for efflux of triclosanPredictive Studies Suggest that the Risk for the Selection of Antibiotic Resistance by Biocides Is Likely Low in Stenotrophomonas maltophiliaGenes required for and effects of alginate overproduction induced by growth of Pseudomonas aeruginosa on Pseudomonas isolation agar supplemented with ammonium metavanadate.Dynamics of Plasmodium falciparum enoyl-ACP reductase and implications on drug discovery.An array of target-specific screening strains for antibacterial discovery.Determination of selectivity and efficacy of fatty acid synthesis inhibitors.Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosisChemical interference of pathogen-associated molecular pattern-triggered immune responses in Arabidopsis reveals a potential role for fatty-acid synthase type II complex-derived lipid signals.Cross-resistance between triclosan and antibiotics in Pseudomonas aeruginosa is mediated by multidrug efflux pumps: exposure of a susceptible mutant strain to triclosan selects nfxB mutants overexpressing MexCD-OprJ.Response of Bacillus subtilis to cerulenin and acquisition of resistance.NB2001, a novel antibacterial agent with broad-spectrum activity and enhanced potency against beta-lactamase-producing strains.
P2860
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P2860
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@en
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@nl
type
label
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@en
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@nl
prefLabel
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@en
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@nl
P2093
P356
P1476
Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis.
@en
P2093
P304
30316-30320
P356
10.1074/JBC.273.46.30316
P407
P577
1998-11-01T00:00:00Z