Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model.
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Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Modelsα-Tocopherol and Hippocampal Neural Plasticity in Physiological and Pathological ConditionsA swell in the armamentarium of antiepileptic drug targetsAlbumin activates astrocytes and microglia through mitogen-activated protein kinase pathways.Minozac treatment prevents increased seizure susceptibility in a mouse "two-hit" model of closed skull traumatic brain injury and electroconvulsive shock-induced seizures.The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia.An adeno-associated virus-based intracellular sensor of pathological nuclear factor-κB activation for disease-inducible gene transfer.Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment.Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation.Exploring the genomic basis of pharmacoresistance in epilepsy: an integrative analysis of large-scale gene expression profiling studies on brain tissue from epilepsy surgeryClosed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment.Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures.MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses.Lipopolysaccharide potentiates hyperthermia-induced seizures.NMDA receptor antagonism with novel indolyl, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy.A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers.Evidence of microglial activation in autism and its possible role in brain underconnectivityA Molecular Approach to Epilepsy Management: from Current Therapeutic Methods to Preconditioning Efforts.Inflammatory aspects of epileptogenesis: contribution of molecular inflammatory mechanisms.Attenuation of traumatic brain injury-induced cognitive impairment in mice by targeting increased cytokine levels with a small molecule experimental therapeutic.Increased CCL2, CCL3, CCL5, and IL-1β cytokine concentration in piriform cortex, hippocampus, and neocortex after pilocarpine-induced seizures.Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology.Transgenerational modification of hippocampus TNF-α and S100B levels in the offspring of rats chronically exposed to morphine during adolescence.Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models.Dietary supplementation with α-tocopherol reduces neuroinflammation and neuronal degeneration in the rat brain after kainic acid-induced status epilepticus.Post-seizure α-tocopherol treatment decreases neuroinflammation and neuronal degeneration induced by status epilepticus in rat hippocampus.Neurobiological Correlates of Alpha-Tocopherol Antiepileptogenic Effects and MicroRNA Expression Modulation in a Rat Model of Kainate-Induced Seizures.Synaptic Failure: Focus in an Integrative View of ALS.Microglial activation: an important process in the onset of epilepsy
P2860
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P2860
Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Enhanced microglial activation ...... in a 'two-hit' seizure model.
@en
Enhanced microglial activation ...... in a 'two-hit' seizure model.
@nl
type
label
Enhanced microglial activation ...... in a 'two-hit' seizure model.
@en
Enhanced microglial activation ...... in a 'two-hit' seizure model.
@nl
prefLabel
Enhanced microglial activation ...... in a 'two-hit' seizure model.
@en
Enhanced microglial activation ...... in a 'two-hit' seizure model.
@nl
P2093
P2860
P1433
P1476
Enhanced microglial activation ...... y in a 'two-hit' seizure model
@en
P2093
Kathleen C Somera-Molina
Linda J Van Eldik
Mark S Wainwright
Sangeetha Nair
P2860
P304
P356
10.1016/J.BRAINRES.2009.05.073
P407
P577
2009-06-06T00:00:00Z