about
A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive conditionA synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.Utilizing past and present mouse systems to engineer more relevant pancreatic cancer modelsMice lacking mitochondrial uncoupling protein are cold-sensitive but not obeseGenetic analysis of Ras signalling pathways in cell proliferation, migration and survival.Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.K-RasV14I recapitulates Noonan syndrome in mice.Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivoLoss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expressionEGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma.Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidationCommon Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis.What we have learned about pancreatic cancer from mouse models.The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice.Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.Chronic pancreatitis and lipomatosis are associated with defective function of ciliary genes in pancreatic ductal cells.Modeling RASopathies with Genetically Modified Mouse Models.Upregulation of miR-21 by Ras in vivo and its role in tumor growth.The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.The impact of the genetic background in the Noonan syndrome phenotype induced by K-Ras(V14I).Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse modelsPancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.Tumour biology: senescence in premalignant tumours.DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.Reply: 'Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer'.Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling.Germline expression of H-Ras(G12V) causes neurological deficits associated to Costello syndrome.H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences.Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.IGF-I induces the uncoupling protein gene expression in fetal rat brown adipocyte primary cultures: role of C/EBP transcription factors.Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.Parp-1genetic ablation inEla-mycmice unveils novel roles for Parp-1 in pancreatic cancerTriiodothyronine induces the expression of the uncoupling protein in long term fetal rat brown adipocyte primary cultures: role of nuclear thyroid hormone receptor expressionp38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiationChronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult MiceTriiodothyronine Induces the Transcription of the Uncoupling Protein Gene and Stabilizes Its mRNA in Fetal Rat Brown Adipocyte Primary CulturesTriiodothyronine induces the expression of the uncoupling protein in long term fetal rat brown adipocyte primary cultures: role of nuclear thyroid hormone receptor expression
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Carmen Guerra
@ast
Carmen Guerra
@en
Carmen Guerra
@es
Carmen Guerra
@nl
Carmen Guerra
@sl
type
label
Carmen Guerra
@ast
Carmen Guerra
@en
Carmen Guerra
@es
Carmen Guerra
@nl
Carmen Guerra
@sl
prefLabel
Carmen Guerra
@ast
Carmen Guerra
@en
Carmen Guerra
@es
Carmen Guerra
@nl
Carmen Guerra
@sl
P106
P21
P31
P496
0000-0002-3891-046X