about
MDM2 and MDMX bind and stabilize the p53-related protein p73Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukaemiaSpecialized roles of the two mitotic cyclins in somatic cells: cyclin A as an activator of M phase-promoting factorMASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activationTimeless Interacts with PARP-1 to Promote Homologous Recombination RepairCyclin A in cell cycle control and cancerCyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damageCharacterization of the cullin and F-box protein partner Skp1Identification of functional domains in the neuronal Cdk5 activator proteinInhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit.Critical differences between isoforms of securin reveal mechanisms of separase regulationSalt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.A roller coaster ride with the mitotic cyclins.Novel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints.Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT.p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells.How many mutant p53 molecules are needed to inactivate a tetramer?Ubiquitination of p53 at multiple sites in the DNA-binding domain.How protein kinases co-ordinate mitosis in animal cells.Aurora B: hooking up with cyclin-dependent kinases.DNA damage checkpoints in nasopharyngeal carcinoma.The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.Cell Cycle Control: A System of Interlinking Oscillators.Label-free enumeration of colorectal cancer cells from lymphocytes performed at a high cell-loading density by using interdigitated ring-array microelectrodes.Tetraploidization increases sensitivity to Aurora B kinase inhibition.Gene down-regulation with short hairpin RNAs and validation of specificity by inducible rescue in mammalian cells.SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A-B56BS69 is involved in cellular senescence through the p53-p21Cip1 pathway.Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint.On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells.BCL-W is a regulator of microtubule inhibitor-induced mitotic cell death.Dovitinib induces mitotic defects and activates the G2 DNA damage checkpoint.Depletion of p31comet protein promotes sensitivity to antimitotic drugs.An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells.CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Randy Poon
@ast
Randy Poon
@en
Randy Poon
@es
Randy Poon
@nl
Randy Poon
@sl
type
label
Randy Poon
@ast
Randy Poon
@en
Randy Poon
@es
Randy Poon
@nl
Randy Poon
@sl
prefLabel
Randy Poon
@ast
Randy Poon
@en
Randy Poon
@es
Randy Poon
@nl
Randy Poon
@sl
P106
P1153
7103097213
P21
P31
P496
0000-0001-5571-6231