Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.
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Autoacetylation of the histone acetyltransferase Rtt109Current chemical biology approaches to interrogate protein methyltransferasesHistone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferasesProtein lysine acetylation by p300/CBPProtein lysine acylation and cysteine succination by intermediates of energy metabolismStructural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106Diverse functionalization of Aurora-A kinase at specified surface and buried sites by native chemical modificationBromodomain-dependent stage-specific male genome programming by BrdtChemical and biological tools for the preparation of modified histone proteinsRegulation of S-adenosylhomocysteine hydrolase by lysine acetylationHistones: at the crossroads of peptide and protein chemistry.Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis.Development of α-helical calpain probes by mimicking a natural protein-protein interaction.Chemical Methods for Encoding and Decoding of Posttranslational ModificationsDynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.Site-specific incorporation of ε-N-crotonyllysine into histonesSelective and Reversible Photochemical Derivatization of Cysteine Residues in Peptides and Proteins.Synthesis of proteins with defined posttranslational modifications using the genetic noncanonical amino acid incorporation approach.Spreading chromatin into chemical biology.Chemical approaches for the detection and synthesis of acetylated proteins.Novel electrostatic mechanism for mode of action by N-acetylated proteins: cell signaling and phosphorylation.Synthesis of post-translationally modified proteins.New assays and approaches for discovery and design of Sirtuin modulators.Acetyl-CoA and the regulation of metabolism: mechanisms and consequences.Synthetic approaches to protein phosphorylation.Chemical and semisynthesis of modified histones.Chemical Protein Modification through Cysteine.A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks.Site-selective protein-modification chemistry for basic biology and drug development.The Cysteine S-Alkylation Reaction as a Synthetic Method to Covalently Modify Peptide Sequences.Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3.Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin.Azalysine analogues as probes for protein lysine deacetylation and demethylation.Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein bindingSite-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus.Chloromethyl-triazole: a new motif for site-selective pseudo-acylation of proteins.Chemical biology approaches for studying posttranslational modifications.Palladium(II)-Catalyzed Site-Selective C(sp3 )-H Alkynylation of Oligopeptides: A Linchpin Approach for Oligopeptide-Drug Conjugation.Proteins with Site-Specific Lysine Methylation.Conversion of Cysteine into Dehydroalanine Enables Access to Synthetic Histones Bearing Diverse Post-Translational Modifications
P2860
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P2860
Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Site-specific introduction of ...... oteins by cysteine alkylation.
@en
Site-specific introduction of ...... oteins by cysteine alkylation.
@nl
type
label
Site-specific introduction of ...... oteins by cysteine alkylation.
@en
Site-specific introduction of ...... oteins by cysteine alkylation.
@nl
prefLabel
Site-specific introduction of ...... oteins by cysteine alkylation.
@en
Site-specific introduction of ...... oteins by cysteine alkylation.
@nl
P2093
P2860
P50
P356
P1476
Site-specific introduction of ...... roteins by cysteine alkylation
@en
P2093
Beverley M Dancy
Blair C Dancy
Katrina Meeth
Marc A Holbert
Mary Katherine Tarrant
Philip A Cole
Robert N Cole
Ronen Marmorstein
Sandrine Curtet
P2860
P304
P356
10.1021/JA103954U
P407
P577
2010-07-01T00:00:00Z