Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.
about
New insights into an X-traordinary viral proteinStructural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolaseLocalization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor proteinVpx is critical for reverse transcription of the human immunodeficiency virus type 2 genome in macrophagesMutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 VprThe Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T CellsCrystal structure of zinc-finger domain of Nanos and its functional implicationsThe mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTPLentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infectionVPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytesFunctional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr.Interaction of human immunodeficiency virus type 2 Vpx and invariant chain.A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)Functional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.Molecular and biological characterization of a replication competent human immunodeficiency type 2 (HIV-2) proviral cloneThe human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.Evolution of the primate lentiviruses: evidence from vpx and vprMutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation.Simian immunodeficiency virus Vpx is imported into the nucleus via importin alpha-dependent and -independent pathwaysIdentification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradationHuman immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells.Progression to AIDS in the absence of a gene for vpr or vpx.The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particlesTargeting foreign proteins to human immunodeficiency virus particles via fusion with Vpr and Vpx.A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particlesMutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.Vpr-induced cell cycle arrest is conserved among primate lentiviruses.Inhibition of human and simian immunodeficiency virus protease function by targeting Vpx-protease-mutant fusion protein into viral particlesDevelopment of a novel anti-HIV-1 agent from within: effect of chimeric Vpr-containing protease cleavage site residues on virus replicationA virion-specific inhibitory molecule with therapeutic potential for human immunodeficiency virus type 1Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles.Molecular biology of the human immunodeficiency virus accessory proteinsVpx of simian immunodeficiency virus is localized primarily outside the virus core in mature virions.Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions.Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.Human immunodeficiency virus type 1 gag-protease fusion proteins are enzymatically active.Dispensable role of the human immunodeficiency virus type 2 Vpx protein in viral replication.Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein.The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophageMolecular characterization of an attenuated human immunodeficiency virus type 2 isolate.
P2860
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P2860
Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.
@en
Isolation and characterization of a novel protein
@nl
type
label
Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.
@en
Isolation and characterization of a novel protein
@nl
prefLabel
Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.
@en
Isolation and characterization of a novel protein
@nl
P2093
P356
P1433
P1476
Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.
@en
P2093
Benveniste RE
Copeland TD
Henderson LE
Oroszlan S
P304
P356
10.1126/SCIENCE.3388031
P407
P577
1988-07-01T00:00:00Z