Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3).
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Crystal Structures of Three Classes of Non-Steroidal Anti-Inflammatory Drugs in Complex with Aldo-Keto Reductase 1C3Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate CancerStructure of AKR1C3 with 3-phenoxybenzoic acid boundCrystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancerIntratumoral steroidogenesis in castration-resistant prostate cancer: a target for therapy.Selective inhibitors of aldo-keto reductases AKR1C1 and AKR1C3 discovered by virtual screening of a fragment libraryHuman hydroxysteroid dehydrogenases and pre-receptor regulation: insights into inhibitor design and evaluation.Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3).Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC).AKR1C3 as a target in castrate resistant prostate cancerAldo-Keto Reductase AKR1C1-AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy.Carbonyl reduction pathways in drug metabolism.Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor.In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3).N-Benzoyl anthranilic acid derivatives as selective inhibitors of aldo-keto reductase AKR1C3.Discovery of anthranilamides as a novel class of inhibitors of neurotropic alphavirus replication.Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review.
P2860
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P2860
Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3).
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Discovery of substituted 3-
@nl
Discovery of substituted 3-(ph ...... teroid dehydrogenase (AKR1C3).
@en
type
label
Discovery of substituted 3-
@nl
Discovery of substituted 3-(ph ...... teroid dehydrogenase (AKR1C3).
@en
prefLabel
Discovery of substituted 3-
@nl
Discovery of substituted 3-(ph ...... teroid dehydrogenase (AKR1C3).
@en
P2093
P2860
P1476
Discovery of substituted 3-(ph ...... teroid dehydrogenase (AKR1C3).
@en
P2093
Adegoke O Adeniji
Barry M Twenter
Jeffrey D Winkler
Michael C Byrns
P2860
P304
P356
10.1016/J.BMCL.2011.01.010
P407
P577
2011-01-07T00:00:00Z