about
Plant tRNA ligases are multifunctional enzymes that have diverged in sequence and substrate specificity from RNA ligases of other phylogenetic originsAnalysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediateFunctional and structural insights revealed by molecular dynamics simulations of an essential RNA editing ligase in Trypanosoma bruceiBiases in small RNA deep sequencing data.Modeling bias and variation in the stochastic processes of small RNA sequencing.T4 RNA ligase 2 truncated active site mutants: improved tools for RNA analysis.RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries.An RNA ligase from Deinococcus radiodurans.Sensitive, multiplex and direct quantification of RNA sequences using a modified RASL assay.Reducing ligation bias of small RNAs in libraries for next generation sequencing.Structure-function analysis of Methanobacterium thermoautotrophicum RNA ligase - engineering a thermostable ATP independent enzyme.Elimination of ligation dependent artifacts in T4 RNA ligase to achieve high efficiency and low bias microRNA capture.Structure-guided mutational analysis of T4 RNA ligase 1.Systematic Mapping of RNA-Chromatin Interactions In Vivo.Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysisDiscovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei.Toward understanding the conformational dynamics of RNA ligationComparative analysis of editosome proteins in trypanosomatidsDiscovery and design of DNA and RNA ligase inhibitors in infectious microorganisms.Diversity and roles of (t)RNA ligases.Mutations of Asp540 and the domain-connecting residues synergistically enhance Pyrococcus furiosus DNA ligase activity.Structure-based mutational study of an archaeal DNA ligase towards improvement of ligation activity.Characterization of polynucleotide kinase/phosphatase enzymes from Mycobacteriophages omega and Cjw1 and vibriophage KVP40.Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli DNA Ligase (LigA).Kinetic mechanism and fidelity of nick sealing by Escherichia coli NAD+-dependent DNA ligase (LigA).Three-dimensional structure model and predicted ATP interaction rewiring of a deviant RNA ligase 2.Kinetic mechanism of nick sealing by T4 RNA ligase 2 and effects of 3'-OH base mispairs and damaged base lesions.Structure-function analysis of yeast tRNA ligase.Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4.Mutational analysis of bacteriophage T4 RNA ligase 1. Different functional groups are required for the nucleotidyl transfer and phosphodiester bond formation steps of the ligation reaction.Genetic and biochemical analysis of the functional domains of yeast tRNA ligase.Characterization of a baculovirus enzyme with RNA ligase, polynucleotide 5'-kinase, and polynucleotide 3'-phosphatase activities.RNA substrate specificity and structure-guided mutational analysis of bacteriophage T4 RNA ligase 2.Structure-guided mutational analysis of the nucleotidyltransferase domain of Escherichia coli NAD+-dependent DNA ligase (LigA).Dual mechanisms whereby a broken RNA end assists the catalysis of its repair by T4 RNA ligase 2.Molecular architecture and ligand recognition determinants for T4 RNA ligase.Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D.Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Structure-function analysis of T4 RNA ligase 2.
@en
Structure-function analysis of T4 RNA ligase 2.
@nl
type
label
Structure-function analysis of T4 RNA ligase 2.
@en
Structure-function analysis of T4 RNA ligase 2.
@nl
prefLabel
Structure-function analysis of T4 RNA ligase 2.
@en
Structure-function analysis of T4 RNA ligase 2.
@nl
P2860
P356
P1476
Structure-function analysis of T4 RNA ligase 2.
@en
P2093
C Kiong Ho
Shenmin Yin
P2860
P304
17601-17608
P356
10.1074/JBC.M300817200
P407
P577
2003-02-27T00:00:00Z