about
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin bindingBinding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor proteinIdentification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensationNuclear organization of DNA replication initiation proteins in mammalian cellsIn vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATPcca1 is required for formation of growth-arrested confluent monolayer of rat 3Y1 cellsIsolation of a novel cDNA whose corresponding mRNA is accumulated in growth-arrested confluent but not in growing sub-confluent rat 3Y1 cellsCdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architectureNucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formationHistone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancersNoncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation.In vivo dynamics of EBNA1-oriP interaction during latent and lytic replication of Epstein-Barr virus.Architecture of replication compartments formed during Epstein-Barr virus lytic replication.Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes.The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.Cloning of a cDNA encoding a human homologue of CDC47, a member of the MCM family.Immunolocalization of hCDC47 protein in normal and neoplastic human tissues and its relation to growth.Cell cycle- and chromatin binding state-dependent phosphorylation of human MCM heterohexameric complexes. A role for cdc2 kinase.Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replicationCdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.E6AP-dependent degradation of DLG4/PSD95 by high-risk human papillomavirus type 18 E6 protein.Regulation of Notch1 gene expression by p53 in epithelial cellsLatent and lytic Epstein-Barr virus replication strategies.Identification of Immunoglobulin Gene Sequences from a Small Read Number of mRNA-Seq Using HybridomasIdentification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.Reactivation of lytic replication from B cells latently infected with Epstein-Barr virus occurs with high S-phase cyclin-dependent kinase activity while inhibiting cellular DNA replication.GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo.Generation of a monoclonal antibody for INI1/hSNF5/BAF47.DNA Replication Origins and Fork Progression at Mammalian TelomeresInvolvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.An in vitro multistep carcinogenesis model for human cervical cancer.Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.TRF2 recruits ORC through TRFH domain dimerization.Preparation of a murine cell line which stably expresses human T lymphotropic virus type I (HTLV-I) env genome products.Cdk2-dependent and -independent pathways in E2F-mediated S phase induction.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Masatoshi Fujita
@ast
Masatoshi Fujita
@en
Masatoshi Fujita
@es
Masatoshi Fujita
@nl
Masatoshi Fujita
@sl
Масатоси Фудзита
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type
label
Masatoshi Fujita
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Masatoshi Fujita
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Masatoshi Fujita
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Masatoshi Fujita
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Masatoshi Fujita
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Масатоси Фудзита
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prefLabel
Masatoshi Fujita
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Masatoshi Fujita
@en
Masatoshi Fujita
@es
Masatoshi Fujita
@nl
Masatoshi Fujita
@sl
Масатоси Фудзита
@ru
P106
P1153
55461661500
P21
P31
P496
0000-0001-6617-2452