Fluoroquinolone and quinazolinedione activities against wild-type and gyrase mutant strains of Mycobacterium smegmatis.
about
Current prospects for the fluoroquinolones as first-line tuberculosis therapyFluoroquinolone-gyrase-DNA complexes: two modes of drug binding.Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridgeBypassing fluoroquinolone resistance with quinazolinediones: studies of drug-gyrase-DNA complexes having implications for drug design.Activity of quinolone CP-115,955 against bacterial and human type II topoisomerases is mediated by different interactions.Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase.Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis.Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance.Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones.Overcoming target-mediated quinolone resistance in topoisomerase IV by introducing metal-ion-independent drug-enzyme interactions.Mechanism of quinolone action and resistance.Synthesis of new quinazolin-2,4-diones as anti-Leishmania mexicana agents.Induction of mycobacterial resistance to quinolone class antimicrobialsBactericidal activity of ACH-702 against nondividing and biofilm Staphylococci.Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery.Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities.DNA Topoisomerases as Targets for Antibacterial Agents.The Use of Biosensors to Explore the Potential of Probiotic Strains to Reduce the SOS Response and Mutagenesis in Bacteria.
P2860
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P2860
Fluoroquinolone and quinazolinedione activities against wild-type and gyrase mutant strains of Mycobacterium smegmatis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Fluoroquinolone and quinazolin ...... ns of Mycobacterium smegmatis.
@en
Fluoroquinolone and quinazolin ...... ns of Mycobacterium smegmatis.
@nl
type
label
Fluoroquinolone and quinazolin ...... ns of Mycobacterium smegmatis.
@en
Fluoroquinolone and quinazolin ...... ns of Mycobacterium smegmatis.
@nl
prefLabel
Fluoroquinolone and quinazolin ...... ns of Mycobacterium smegmatis.
@en
Fluoroquinolone and quinazolin ...... ns of Mycobacterium smegmatis.
@nl
P2093
P2860
P356
P1476
Fluoroquinolone and quinazolin ...... ins of Mycobacterium smegmatis
@en
P2093
Arkady Mustaev
Kalyan Chavda
Karl Drlica
Kevin R Marks
Muhammad Malik
Robert J Kerns
P2860
P304
P356
10.1128/AAC.00033-11
P407
P50
P577
2011-03-07T00:00:00Z